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SULT1B1

From Wikipedia, the free encyclopedia
SULT1B1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSULT1B1, ST1B1, ST1B2, SULT1B2, sulfotransferase family 1B member 1
External IDsOMIM: 608436; MGI: 2136282; HomoloGene: 69169; GeneCards: SULT1B1; OMA:SULT1B1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014465

NM_019878
NM_001356943
NM_001382837

RefSeq (protein)

NP_055280

NP_063931
NP_001343872
NP_001369766

Location (UCSC)Chr 4: 69.72 – 69.79 MbChr 5: 87.66 – 87.69 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sulfotransferase family cytosolic 1B member 1 is an enzyme that in humans is encoded by the SULT1B1 gene.[5][6][7]

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of all of the other SULT1 genes.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173597Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029269Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Meinl W, Glatt H (Nov 2001). "Structure and localization of the human SULT1B1 gene: neighborhood to SULT1E1 and a SULT1D pseudogene". Biochem Biophys Res Commun. 288 (4): 855–62. doi:10.1006/bbrc.2001.5829. PMID 11688987.
  6. ^ Fujita K, Nagata K, Ozawa S, Sasano H, Yamazoe Y (Feb 1998). "Molecular cloning and characterization of rat ST1B1 and human ST1B2 cDNAs, encoding thyroid hormone sulfotransferases". J Biochem. 122 (5): 1052–61. doi:10.1093/oxfordjournals.jbchem.a021846. PMID 9443824.
  7. ^ a b "Entrez Gene: SULT1B1 sulfotransferase family, cytosolic, 1B, member 1".

Further reading

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