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Protein-coding gene in the species Homo sapiens
U2 small nuclear ribonucleoprotein B is a protein that in humans is encoded by the SNRPB2 gene .[ 5] [ 6]
The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene.[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000125870 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000008333 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Habets WJ, Sillekens PT, Hoet MH, Schalken JA, Roebroek AJ, Leunissen JA, van de Ven WJ, van Venrooij WJ (May 1987). "Analysis of a cDNA clone expressing a human autoimmune antigen: full-length sequence of the U2 small nuclear RNA-associated B" antigen" . Proc Natl Acad Sci U S A . 84 (8): 2421–5. Bibcode :1987PNAS...84.2421H . doi :10.1073/pnas.84.8.2421 . PMC 304663 . PMID 2951739 .
^ a b "Entrez Gene: SNRPB2 small nuclear ribonucleoprotein polypeptide B" .
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