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Rubredoxin—NAD(P)(+) reductase

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rubredoxin—NAD(P)+ reductase
Identifiers
EC no.1.18.1.4
CAS no.114514-31-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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In enzymology, a rubredoxin—NAD(P)+ reductase (EC 1.18.1.4) is an enzyme that catalyzes the chemical reaction

reduced rubredoxin + NAD(P)+ oxidized rubredoxin + NAD(P)H + H+

The 3 substrates of this enzyme are reduced rubredoxin, NAD+, and NADP+, whereas its 4 products are oxidized rubredoxin, NADH, NADPH, and H+.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on iron-sulfur proteins as donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is rubredoxin:NAD(P)+ oxidoreductase. Other names in common use include rubredoxin-nicotinamide adenine dinucleotide (phosphate) reductase, rubredoxin-nicotinamide adenine, dinucleotide phosphate reductase, NAD(P)+-rubredoxin oxidoreductase, and NAD(P)H-rubredoxin oxidoreductase. This enzyme participates in fatty acid metabolism.

See also

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References

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  1. ^ Petitdemange H, Blusson H, Gay R (September 1981). "Detection of NAD(P)H--rubredoxin oxidoreductases in Clostridia". Analytical Biochemistry. 116 (2): 564–70. doi:10.1016/0003-2697(81)90403-6. PMID 6274224.
  2. ^ Ma K, Adams MW (September 1999). "A hyperactive NAD(P)H:Rubredoxin oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus". Journal of Bacteriology. 181 (17): 5530–3. PMC 94068. PMID 10464233.
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