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Retrovirus direct repeat 1 (dr1)

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Retrovirus direct repeat 1 (dr1)
Predicted secondary structure and sequence conservation of Retro_dr1
Identifiers
SymbolRetro_dr1
RfamRF00214
Other data
RNA typeCis-reg
Domain(s)Viruses
SOSO:0000233
PDB structuresPDBe

The direct repeat 1 (dr1) element is an RNA element commonly found in the 3' UTR of Avian sarcoma, Rous sarcoma and Avian leukosis viruses (Alpharetroviruses and Avian type C retroviruses). dr1 is required for efficient viral replication and is thought to be involved in genomic RNA packaging although this may not be its only role.[1]

References

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  1. ^ Aschoff JM, Foster D, Coffin JM (September 1999). "Point mutations in the avian sarcoma/leukosis virus 3' untranslated region result in a packaging defect". Journal of Virology. 73 (9): 7421–7429. doi:10.1128/JVI.73.9.7421-7429.1999. PMC 104269. PMID 10438832.
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