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Protein-coding gene in the species Homo sapiens
Ras GTPase-activating protein nGAP is an enzyme that in humans is encoded by the RASAL2 gene .[ 5] [ 6]
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases . The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.[ 6]
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