Phenylaminotetralin
Appearance
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Names | |
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IUPAC name
(2S,4R)-N,N-dimethyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-2-amine
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Identifiers | |
3D model (JSmol)
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PubChem CID
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Properties | |
C18H21N | |
Molar mass | 251.373 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Phenylaminotetralins are novel histamine receptor ligands. Binding assays determined that (-)-trans-H2-PAT possessed the strongest binding affinity at the histamine H1 receptor.[1]
References
[edit]- ^ Booth, RG; Moniri, NH; Bakker, RA; Choksi, NY; Nix, WB; Timmerman, H; Leurs, R (July 2002). "A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors". The Journal of Pharmacology and Experimental Therapeutics. 302 (1): 328–36. doi:10.1124/jpet.302.1.328. PMID 12065734.