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Peter Currie (scientist)

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Peter D. Currie is an Australian developmental and stem cell biologist.[1] He is a professor and director of the Australian Regenerative Medicine Institute at Monash University.

Research and career

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Currie studied at Monash University. He received his PhD in Drosophila genetics from Syracuse University, New York, USA, in 1993. He undertook postdoctoral training in zebrafish development at the Imperial Cancer Research Fund (now Cancer Research UK) in London, UK. He has worked as an independent laboratory head at the UK Medical Research Council Human Genetics Unit in Edinburgh, UK and from 2003 onwards at the Victor Chang Cardiac Research Institute in Sydney, Australia where he headed a research programme focused on skeletal muscle development and regeneration.

In 2008 he became Deputy Director of the Australian Regenerative Medicine Institute (ARMI) at Monash University in Melbourne, Australia, and was appointed Director of Research in 2016.[2] He currently is group leader[3] and also an Australian EMBL partnership laboratory head.[4] He is a recipient of a European Molecular Biology Organization Young Investigators Award and a Wellcome Trust International Research Fellowship and currently is a Senior Principal Research Fellow with the National Health and Medical Research Council in Australia.

Currie investigates the genetic basis of skeletal muscle stem cell action during development, evolution, regeneration and disease.[5] His key discoveries utilise several models, chiefly the zebrafish, to define the genetic and evolutionary basis for muscle formation and growth throughout vertebrate phylogeny.[6][7][8][9] He has played a key role globally in developing zebrafish as a disease model for human muscle disease and regeneration biology.[10][11] He has also been instrumental in establishing shark embryology as a modern evolutionary paradigm to understand the evolutionary origins of the vertebrate body plan.[12]

Awards and honours

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Australian Museum Eureka Prize 2015 (with Phong Nguyen and Georgina Hollway)[13]

Fellow of the Australian Academy of Science (FAA) since 2020[14][15]

References

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  1. ^ "Peter Currie". scholar.google.co.uk. Retrieved 2023-09-26.
  2. ^ Digital, Arcadian (2016-02-04). "New ARMI Director Announced: Professor Peter Currie to take the lead". Australian Regenerative Medicine Institute. Retrieved 2023-09-26.
  3. ^ "Currie Group". Australian Regenerative Medicine Institute. Retrieved 2023-09-26.
  4. ^ "Peter Currie". EMBL Australia. Retrieved 2023-09-26.
  5. ^ Lieschke, Graham J.; Currie, Peter D. (May 2007). "Animal models of human disease: zebrafish swim into view". Nature Reviews. Genetics. 8 (5): 353–367. doi:10.1038/nrg2091. ISSN 1471-0056. PMID 17440532.
  6. ^ Masselink, Wouter; Cole, Nicholas J.; Fenyes, Fruzsina; Berger, Silke; Sonntag, Carmen; Wood, Alasdair; Nguyen, Phong D.; Cohen, Naomi; Knopf, Franziska; Weidinger, Gilbert; Hall, Thomas E.; Currie, Peter D. (July 2016). "A somitic contribution to the apical ectodermal ridge is essential for fin formation". Nature. 535 (7613): 542–546. Bibcode:2016Natur.535..542M. doi:10.1038/nature18953. ISSN 1476-4687.
  7. ^ Gurevich, David B.; Nguyen, Phong Dang; Siegel, Ashley L.; Ehrlich, Ophelia V.; Sonntag, Carmen; Phan, Jennifer M. N.; Berger, Silke; Ratnayake, Dhanushika; Hersey, Lucy; Berger, Joachim; Verkade, Heather; Hall, Thomas E.; Currie, Peter D. (2016-07-08). "Asymmetric division of clonal muscle stem cells coordinates muscle regeneration in vivo". Science. 353 (6295). doi:10.1126/science.aad9969. ISSN 0036-8075.
  8. ^ Nguyen, Phong Dang; Gurevich, David Baruch; Sonntag, Carmen; Hersey, Lucy; Alaei, Sara; Nim, Hieu Tri; Siegel, Ashley; Hall, Thomas Edward; Rossello, Fernando Jaime; Boyd, Sarah Elizabeth; Polo, Jose Maria; Currie, Peter David (July 2017). "Muscle Stem Cells Undergo Extensive Clonal Drift during Tissue Growth via Meox1-Mediated Induction of G2 Cell-Cycle Arrest". Cell Stem Cell. 21 (1): 107–119.e6. doi:10.1016/j.stem.2017.06.003. ISSN 1934-5909. PMID 28686860.
  9. ^ Berger, Joachim; Berger, Silke; Li, Mei; Jacoby, Arie S.; Arner, Anders; Bavi, Navid; Stewart, Alastair G.; Currie, Peter D. (January 2018). "In Vivo Function of the Chaperonin TRiC in α-Actin Folding during Sarcomere Assembly". Cell Reports. 22 (2): 313–322. doi:10.1016/j.celrep.2017.12.069. ISSN 2211-1247.
  10. ^ Hall, T. E.; Wood, A. J.; Ehrlich, O.; Li, M.; Sonntag, C. S.; Cole, N. J.; Huttner, I. G.; Sztal, T. E.; Currie, P. D. (2019-11-15). "Cellular rescue in a zebrafish model of congenital muscular dystrophy type 1A". npj Regenerative Medicine. 4 (1): 1–13. doi:10.1038/s41536-019-0084-5. ISSN 2057-3995. PMC 6858319.
  11. ^ Ratnayake, Dhanushika; Nguyen, Phong D.; Rossello, Fernando J.; Wimmer, Verena C.; Tan, Jean L.; Galvis, Laura A.; Julier, Ziad; Wood, Alasdair J.; Boudier, Thomas; Isiaku, Abdulsalam I.; Berger, Silke; Oorschot, Viola; Sonntag, Carmen; Rogers, Kelly L.; Marcelle, Christophe (March 2021). "Macrophages provide a transient muscle stem cell niche via NAMPT secretion". Nature. 591 (7849): 281–287. Bibcode:2021Natur.591..281R. doi:10.1038/s41586-021-03199-7. ISSN 1476-4687.
  12. ^ Tzung, Keh-Weei; Lalonde, Robert L.; Prummel, Karin D.; Mahabaleshwar, Harsha; Moran, Hannah R.; Stundl, Jan; Cass, Amanda N.; Le, Yao; Lea, Robert; Dorey, Karel; Tomecka, Monika J.; Zhang, Changqing; Brombacher, Eline C.; White, William T.; Roehl, Henry H. (June 2023). "A median fin derived from the lateral plate mesoderm and the origin of paired fins". Nature. 618 (7965): 543–549. Bibcode:2023Natur.618..543T. doi:10.1038/s41586-023-06100-w. ISSN 1476-4687. PMC 10266977.
  13. ^ News, Opening Hours 9am-5pm Mon-Sun9am-9pm WedClosed Christmas Day Address 1 William StreetSydney NSW 2010 Australia Phone +61 2 9320 6000 www australian museum Copyright © 2023 The Australian Museum ABN 85 407 224 698 View Museum. "2015 University of New South Wales Eureka Prize for Scientific Research". The Australian Museum. Retrieved 2023-09-26. {{cite web}}: |last= has generic name (help)CS1 maint: numeric names: authors list (link)
  14. ^ "Australia's top scientists elected as Fellows of the Academy | Australian Academy of Science". www.science.org.au. Retrieved 2023-09-26.
  15. ^ "Peter Currie". www.science.org.au. Retrieved 2023-09-26.
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