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NUDT12

From Wikipedia, the free encyclopedia
NUDT12
Identifiers
AliasesNUDT12, nudix hydrolase 12
External IDsOMIM: 609232; MGI: 1915243; HomoloGene: 44188; GeneCards: NUDT12; OMA:NUDT12 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001300741
NM_031438

NM_026497
NM_001368393

RefSeq (protein)

NP_001287670
NP_113626

NP_080773
NP_001355322

Location (UCSC)Chr 5: 103.55 – 103.56 MbChr 17: 59.31 – 59.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Peroxisomal NADH pyrophosphatase NUDT12 is an enzyme that in humans is encoded by the NUDT12 gene.[5][6]

Nucleotides are involved in numerous biochemical reactions and pathways within the cell as substrates, cofactors, and effectors.

Nudix hydrolases, such as NUDT12, regulate the concentrations of individual nucleotides and of nucleotide ratios in response to changing circumstances (Abdelraheim et al., 2003).[supplied by OMIM][6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000112874Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024228Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  6. ^ a b "Entrez Gene: NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12".

Further reading

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