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Misophonia

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Misophonia
Other namesselective sound sensitivity syndrome,[1] misophonic disorder,[2][3] select sound sensitivity syndrome,[4] soft sound sensitivity symptom,[4] sound-rage[4][5][6]
Pronunciation
SpecialtyPsychiatry, clinical psychology, audiology
Complicationssocial isolation, extreme trigger avoidance, relationship difficulties, anxiety (particularly phonophobia), maladaptive coping strategies (including suicidality, aggression, and self-harm)[4][7][8]
Usual onsetVariable (childhood through adulthood), with most common onset in childhood/early adolescence[7]
CausesNeuropsychological and perceptual processing differences of unclear etiology[4][9]
TreatmentMost evidence for specialized forms of cognitive-behavioral therapy,[10][11][12] with extremely limited (case report/series-level) evidence for other psychotherapy modalities, Tinnitus Retraining Therapy, and certain medications.[11][12]

Misophonia (or selective sound sensitivity syndrome) is a disorder of decreased tolerance to specific sounds or their associated stimuli, or cues. These cues, known as "triggers", are experienced as unpleasant or distressing and tend to evoke strong negative emotional, physiological, and behavioral responses not seen in most other people.[8] Misophonia and the behaviors that people with misophonia often use to cope with it (such as avoidance of "triggering" situations or using hearing protection) can adversely affect the ability to achieve life goals, communicate effectively, and enjoy social situations.[4][7] Originating within the field of audiology in 2001,[13] the condition remained largely undescribed in the clinical and research literature until 2013, when a group of psychiatrists at Amsterdam University Medical Center published a detailed misophonia case series and proposed the condition as a "new psychiatric disorder" with defined diagnostic criteria.[14] At present, misophonia is not listed as a diagnosable condition in the DSM-5-TR, ICD-11, or any similar manual,[8][15][16][17] making it difficult for most people with the condition to receive official clinical diagnoses of misophonia or billable medical services. An international panel of misophonia experts has rigorously established a consensus definition of misophonia as a medical condition,[8] and since its initial publication in 2022, this definition has been widely adopted by clinicians and researchers studying the disorder.[18][19]

When confronted with specific "trigger" stimuli, people with misophonia experience a range of negative emotions, most notably anger, extreme irritation, disgust, anxiety, and sometimes rage.[8] The emotional response is often accompanied by a range of physical symptoms (e.g., muscle tension, increased heart rate, and sweating) that may reflect activation of the fight-or-flight response.[8] Unlike the discomfort seen in hyperacusis, misophonic reactions do not seem to be elicited by the sound's loudness but rather by the trigger's specific pattern or meaning to the hearer.[20][21][22] Many people with misophonia cannot trigger themselves with self-produced sounds, or if such sounds do cause a misophonic reaction, it is substantially weaker than if another person produced the sound.[7][8]

Misophonic reactions can be triggered by many different auditory, visual, and audiovisual stimuli,[8] most commonly mouth/nose/throat sounds (particularly those produced by chewing or eating/drinking), repetitive sounds produced by other people or objects, and sounds produced by animals.[7][8] The term misokinesia has been proposed to refer specifically to misophonic reactions to visual stimuli, often repetitive movements made by others.[14][23] Once a trigger stimulus is detected, people with misophonia may have difficulty distracting themselves from the stimulus and may experience suffering, distress, and/or impairment in social, occupational, or academic functioning.[8] Many people with misophonia are aware that their reactions to misophonic triggers are disproportionate to the circumstances,[8] and their inability to regulate their responses to triggers can lead to shame, guilt, isolation, and self-hatred, as well as worsening hypervigilance about triggers, anxiety, and depression.[24][25][26] Studies have shown that misophonia can cause problems in school, work, social life, and family.[18] In the United States, misophonia is not considered one of the 13 disabilities recognized under the Individuals with Disabilities Education Act (IDEA) as eligible for an individualized education plan,[27] but children with misophonia can be granted school-based disability accommodations under a 504 plan.[28]

The expression of misophonia symptoms varies, as does their severity, which can range from mild and sub-clinical to severe and highly disabling.[2][8] The reported prevalence of clinically significant misophonia varies widely across studies due to the varied populations studied and methods used to determine whether a person meets diagnostic criteria for the condition.[29] But three studies that used probability-based sampling methods estimated that 4.6–12.8% of adults may have misophonia that rises to the level of clinical significance.[30][31][32] Misophonia symptoms are typically first observed in childhood or early adolescence, though the onset of the condition can be at any age.[7][8] Treatment primarily consists of specialized cognitive-behavioral therapy,[11] with limited evidence to support any one therapy modality or protocol over another and some studies demonstrating partial or full remission of symptoms with this or other treatment, such as psychotropic medication.[12]

Terminology and origins of the concept

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Pawel Jastreboff and Margaret M. Jastreboff coined the term "misophonia" in 2001 with the assistance of Guy Lee,[33][34] introducing it in their article "Hyperacusis",[35] with further explanation in the International Tinnitus and Hyperacusis Society's ITHS Newsletter.[13]

"Misophonia" comes from the Ancient Greek words μῖσος (IPA: /mîː.sos/), meaning "hate", and φωνή (IPA: /pʰɔː.nɛ̌ː/), meaning "voice" or "sound", loosely translating to "hate of sound", and was coined to differentiate the condition from other forms of decreased sound tolerance, such as hyperacusis (hypersensitivity to certain frequencies and volume ranges) and phonophobia (fear of sounds).[6][36][13]

The term "misophonia" was first used in a peer-reviewed journal in 2002.[37] Before that, the disorder was more commonly called "selective sound sensitivity syndrome", or "4S", a term coined by audiologist Marsha Johnson.[18] Other names formerly used for the condition include "soft sound sensitivity symptom", "select sound sensitivity syndrome", "decreased sound tolerance", and "sound-rage".[4]

In their seminal 2013 case series of patients with misophonia, Schröder and colleagues coined the term "misokinesia" (a term analogous to misophonia translating to "hatred of movement")[14] to describe misophonia-like reactions that occur when people are "triggered" by specific repetitive visual stimuli, such as another person's foot shaking, fingers tapping, or gum chewing.[23] Other authors have proposed "Conditioned Aversive Response Disorder" (C.A.R.D.) as a more suitable name, which seeks to incorporate both auditory and non-auditory aspects of misophonia/misokinesia into a single condition.[38]

Adopting DSM-5-like terminology, some research groups have also advocated the term "misophonic disorder"[2] to distinguish clinically significant and disabling misophonia from what they term "misophonic reactions" (i.e., sub-clinical manifestations of misophonia that do not cause marked distress or substantially impair a person's daily life, relationships, or activities).[2]

Notably, of the above terms, only "misophonia" is widely used by researchers, clinicians, and sufferers of the condition. It is the primary term used for the condition in mainstream journalistic coverage[39][40][41][42] and by the primary philanthropic agency funding research into it (The Misophonia Research Fund [MRF]),[43] and the term selected for use in an (MRF-funded) project to derive a field-wide consensus definition of the condition for clinical and research use.[8]

Signs and symptoms

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Misophonia is a disorder of sound tolerance characterized by extreme and disproportionate emotional reactions to specific sounds (or less commonly, visual stimuli) in one's environment, termed "triggers."[8] Trigger stimuli are experienced as extremely unpleasant or distressing and tend to evoke a "misophonic reaction" that consists of both unpleasant negative emotions (i.e., extreme irritation, anger, anxiety, or disgust; less commonly rage or panic) and increased sympathetic arousal (manifested in physical symptoms such as muscle tension, increased heart rate, and sweating).[7][8]

Trigger stimuli are highly varied and sometimes idiosyncratic, but certain stimuli such as chewing and other oronasal sounds are among the most commonly reported triggers in both clinically referred and population-based samples.[7][8] The Duke Misophonia Questionnaire,[44] a commonly used misophonia symptom measure, groups misophonia triggers into the following categories:

  • People making mouth sounds while eating or drinking (e.g., chewing, crunching, slurping).
  • People making nasal/throat sounds (e.g., sniffing, sneezing, nose-whistling, coughing, throat-clearing).
  • People making mouth sounds when not eating (e.g., making the "tsk" sound, heavy breathing, snoring, whistling).
  • People making repetitive sounds (e.g., typing, tapping nails on table, pen clicking, writing, construction work, using machinery).
  • Rustling or tearing objects (e.g., paper, plastic).
  • Speech sounds (e.g., "p" sounds, hissing "s" sounds, someone speaking with a lisp, high-pitched voices).
  • Body or joint sounds (e.g., snapping fingers, cracking joints, jaw clicking).
  • Rubbing sounds (e.g., hands on pants, hands against one another, Styrofoam rubbing together).
  • Stomping or loud walking (e.g., heels clicking, flip flops, etc.).
  • Muffled sounds (e.g., voices separated by a wall, TV/music in another room).
  • People talking in the background (e.g., phone calls in public, many people talking at once).
  • Repetitive or continuous sounds not made by a person (e.g., clock ticking, air conditioner humming, water running).
  • Animals making repetitive sounds (e.g., licking, chirping, barking, eating, drinking).
  • Seeing someone making or about to make a sound that bothers you, even if you can't hear it (e.g., seeing someone reach into a bag of chips, seeing someone eating on TV with the volume off).
  • Hearing any sound from selective despised individuals or specific races. (e.g., hearing verbal conversation from hated neighbors).

Although less well studied, reported visual triggers in misokinesia include another person's repetitive movements (foot/leg shaking, arms swinging, hands rubbing together, hair twirling, fidgeting), as well as the sight of an auditory trigger that one cannot actually hear (such as someone chewing with their mouth open or tapping their fingers on a desk).[7][8][23]

Reactions to triggers can range from mild (extreme irritation, anxiety, disgust, and/or physical discomfort) to severe (anger, rage, hatred, fear, panic, and/or profound emotional distress).[8] A number of physical symptoms may also accompany the misophonic response, including muscle tension, increased heart rate, sweating, and a feeling of pressure in one's body.[7][8][18] Other idiosyncratic physical and cognitive symptoms are also possible.[7][18]

The five dimensions of cognitive-behavioral responses to "triggers", as empirically derived from the "S-Five" (another misophonia questionnaire that was used in the first large-scale prevalence study of the condition in the UK),[45][46][47] are as follows:

  • Internalizing appraisals such as self-critical thoughts, feeling guilty about one's reactions, and feeling ashamed for reacting to triggers
  • Externalizing appraisals such as blaming others for making triggering sounds, feeling that others are being selfish or disrespectful, and believing that specific sounds are "just bad manners" and should never be made by anyone
  • Anxiety/avoidance responses such as isolating oneself, moving away from the sound, or limiting opportunities to avoid potential trigger exposure
  • Feeling threatened/overwhelmed such as feeling trapped, having thoughts of helplessness, or panicking when one can't escape a trigger
  • Aggressive outbursts such as yelling, screaming, pushing, hitting, throwing things, or (rarely in adults) becoming physically violent

People with misophonia, particularly adults, are typically aware that their emotional reactions and behaviors in response to triggers are disproportionate to the situation,[18] and this frequently causes some degree of internal conflict due to a desire to suppress these reactions.[24]

The first misophonic reaction typically occurs when a person is young, often between the ages of 9 and 13.[7] But misophonia can have an onset at any age, with cases as young as two years old and a number of adult-onset cases reported in the literature.[18][7] The initial misophonic reaction will often originate from someone in a close relationship or a pet.[48]

Fear and anxiety associated with trigger sounds can cause people with this condition to avoid important social and other interactions that may expose them to these sounds.[7] This avoidance and other behaviors can make it harder for them to achieve their goals and enjoy interpersonal interactions.[6][26] It can also have a significant adverse effect on their careers and relationships.[18] Many people with misophonia experience worsening mental health, and some develop psychopathology secondary to their misophonia, including depression, anxiety, phonophobia, self-harm behaviors, and suicidality.[18][26][49][50]

Mechanism

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Misophonia's mechanism is not yet fully understood, and all proposed causes of the disorder are hypothesized based on a combination of clinical observation and the limited existing empirical research.[4] Although misophonia is a disorder of sound tolerance, work to date has not typically demonstrated any peripheral audiologic abnormalities in people with the condition,[51][52][53] suggesting that any "auditory" abnormalities may be caused by a dysfunction of the central auditory system or other parts of the brain that govern "higher-order" perceptor or cognition, rather than the ears per se.[17]

The "neurophysiological" (Jastreboff) model

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The first mechanistic theory of misophonia, proposed by Jastreboff and Jastreboff in 2014,[54][55] is based on the authors' clinical experience and little empirical data. This model, which the authors call the "neurophysiological model",[55] seeks to contrast misophonia with hyperacusis, another disorder of sound tolerance that primarily manifests as excessive loudness perception (or the experience of physical pain in one's ears or head) in response to soft or moderate-intensity everyday sounds.[19][56] The Jastreboffs' neurophysiological model posits that the fundamental difference between misophonia and hyperacusis is that decreased sound tolerance in hyperacusis is closely coupled to the physical properties of the sound stimulus (i.e., intensity, frequency) while, in misophonia, decreased tolerance of "trigger" sounds has little to do with acoustic properties (beyond louder sounds perhaps being easier to perceive and respond to)[55] and arguably depends almost exclusively on the meaning of the sound(s) to a given person.[54][55][57] Its creators have used this model to explain certain aspects of the misophonia phenotype, such as that most people with misophonia do not present with peripheral hearing loss and that context (including whether a trigger is produced by oneself) plays a large role in response to a trigger sound.[55][57]

Although entirely speculative and not based on any empirical neuroscientific data on misophonia, the "neurophysiologic" model also postulates several putative neural mechanisms for the condition from a systems neuroscience perspective.[57] Namely, when processing a trigger stimulus, the brain's central auditory system is thought to have enhanced functional connections with its limbic and autonomic control areas, and downstream overactivity of these areas is theorized to be responsible for the excessive emotional responses and certain physical symptoms of the condition, respectively.[55] These preliminary neuroscientific hypotheses form the basis of the Jastreboffs' signature intervention for sound tolerance conditions (Tinnitus Retraining Therapy, an unproven combination of structured counseling and sound therapy originally developed for tinnitus and now available in modified form to treat misophonia).[54][57]

Notably, there has been relatively little empirical support for the central neuroscientific hypotheses of the neurophysiologic model. Although there has been a relative lack of neuroimaging research on misophonia thus far, functional connectivity between auditory cortical and limbic or autonomic control areas is not typically increased either at rest or during the experience of trigger sound perception.[9] Though many of these same limbic and autonomic control areas may still be relevant in the pathophysiology of misophonia (with anterior insula being one of the most strongly implicated nodes thus far),[9] recent reviews of human neuroimaging research in this condition[9][58] indicate that (a) their activation may be driven by other pathways than simple auditory→limbic or auditory→limbic→autonomic hyper-connectivity and (b) additional structures outside of the Jastreboffs' model (such as premotor cortex)[59] may play a central role in this disorder. The "neurophysiologic" model has also been criticized by other theorists for its vagueness and unwillingness to specify the specific neural structures/processes involved in the "limbic system" portion of the model, as well as its inability to account for non-sound trigger stimuli.

The "action perception" (Berger-Gander-Kumar) model

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A more recently developed model of misophonia was published by neuroscientist Sukhbinder Kumar and colleagues at the University of Iowa in 2024.[58] This model, not formally named by the authors but termed the "action perception" model of misophonia by other researchers using it[60] (alternatively the Berger-Gander-Kumar model), sought to build on the perceived shortcomings of earlier models[54][3] by (a) explicitly incorporating more up-to-date empirical findings in the behavioral, clinical and neuroimaging literature on misophonia, (b) providing explanations for the presence of non-auditory (i.e., visual) and multi-sensory trigger stimuli, and (c) considering perspectives from social cognitive theory and social neuroscience in the broader theory. Although the action perception model is consistent with many of the findings in the misophonia neuroimaging literature, it is important to note that it was generated specifically to explain those findings and therefore represents something of a "just-so story" until its predictions can be empirically validated.[58][61][62]

Based on what is known from neuroimaging and behavioral studies of misophonia, the action perception model conceptualizes the disorder as follows:[58]

  • Sensory information about any stimulus travels from the ear (eye in the case of visual information) through lemniscal/non-lemniscal auditory pathways (or analogous visual pathways) to arrive at and be processed by primary and higher-level auditory cortex (visual cortex).
  • Information is transmitted from a sensory cortex (auditory or visual) to the (pre)motor cortex to form a motor representation of a given action (putatively related to the human "mirror neuron" system).[58]
  • Under pathological conditions (e.g., when an individual with misophonia hears a sound that "triggers" them):
    • The strength or quality of the "motor representation" may be fundamentally different than in non-misophonic people, as demonstrated by hyperactivity of regions responsible for creating these representations.[59][63]
    • The aberrant motor representation conveys an abnormally strong signal to the (anterior) insular cortex, which is then hyperactive relative to non-misophonic controls.[59]
    • Although it is less clear whether this pathway is aberrant or hyperactive due to mixed/limited empirical findings,[58] the insula communicates this signal to (a) the amygdala (putatively responsible for the extreme emotional responses during a misophonic reaction) and (b) autonomic control centers such as the periaqueductal gray and several hypothalamic nuclei (putatively responsible for physiologic aspects of a misophonic reaction, such as changes in heart rate, skin conductance, and potentially other subjective symptoms of being triggered).
  • Though the action perception model denotes the "information flow" through the central nervous system as unidirectional, the authors note that more complex bidirectional interactions between the various nodes of the implicated brain network are likely.[58]

The action perception model arguably represents a major advance over previous theoretical work in this area, particularly in its ability to explain the neuroimaging data on misophonia published before 2024, when the theory was first proposed.[58] Additionally, by focusing on higher-order "motor representations" of objects/actions that are abstracted from their initial sensory information and represented in association cortex (i.e., motor/premotor and limbic areas), the model can be applied to both the auditory and non-auditory triggers of misophonia (i.e., misokinesia) just as easily.[58] But the action perception model appears to apply only to misophonic reactions to human-generated trigger sounds.[38] The action perception model appears consistent with certain clinical features of misophonia, such as the extreme context-specificity of the condition, given that the perceived (even if incorrectly perceived) source of the sound[64] and whether the source can be identified[65] appear to be among the largest drivers of the severity of a given misophonic reaction.[58] Last, although still largely speculative, the action perception model provides an explanation for the peculiar observation that many people with misophonia (46.7% of this population in a recent study by Kumar's group)[66] engage in mimicry (deliberate or unconscious imitation of the trigger sound). As the anterior insula is engaged when counter-imitating an action (i.e., performing the opposite of the imitated movement),[67] Kumar and colleagues theorize that this mimicry conveys an "error signal" that helps inhibit the hyperactive insular cortex involved in the triggering process, thereby reducing the intensity of the misophonic response.[58][66]

Despite its apparent success in explaining findings in the misophonia literature, the action perception model's predictions are largely untested, and many aspects of the model rely on empirical studies with substantial methodological limitations.[58] The basic neural mechanisms of action perception, mimicry, and the role (if any) of the "human mirror neuron system" within a broader social cognition framework in non-clinical populations must be further explored.[58] The role of other co-occurring conditions, particularly those such as autism that are known to both affect social cognition and cooccur with misophonia at exceptionally high rates,[60][68] is also an area for future research to explore and test the model.[58] The evidence supporting the action perception model is essentially correlational, not causal;[38] that is, it is unclear whether motor representations cause misophonic reactions or misophonia is a primarily auditory experience sometimes accompanied by motor representations.

Diagnosis and assessment

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In 2022, clinical and scientific leaders convened to create a consensus definition of misophonia,[8] agreeing that it is a disorder of decreased tolerance to specific sounds and their associated stimuli. Before this consensus definition was reached, scholars and clinicians debated how to describe and define misophonia, which has limited comparison of study cohorts and hampered the development of standard diagnostic criteria.[8] The consensus definition is still not universally accepted by misophonia experts.[55]

Misophonia is distinguished from hyperacusis, which is not specific to a given sound and does not involve a similar strong reaction, and from phonophobia, which is a fear of loud sounds,[48] but it may occur with either.[69] There are no standard diagnostic criteria,[15][48] and many doctors are unaware of the disorder.[8]

Studies show that misophonia often has related comorbid conditions, including anxiety disorders, post-traumatic stress disorder,[70] OCD,[71][72][73] and depressive disorders.[74][75] Some research supports the belief that misophonia is genetic, but more research is needed.[76] It appears that misophonia can occur on its own or along with other health, developmental, and psychiatric problems.[8] When attempting to diagnose a patient with misophonia, doctors sometimes mistake its symptoms for an anxiety disorder, bipolar disorder, or obsessive-compulsive disorder.[8]

Despite misophonia's relative phenotypic distinctiveness, it has been suggested that it belongs to the spectrum of obsessive-compulsive-and-related disorders.[77][16][18] Indeed, distinguishing certain elements of misophonia from those of obsessive-compulsive disorder and obsessive-compulsive personality disorder may be difficult, as many features often overlap.[78][79][80][81][82]

Classification

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The diagnosis of misophonia is not recognized in the DSM-5-TR or the ICD-11, and it is not classified as a hearing or psychiatric disorder.[48] It may be a form of sound–emotion synesthesia, and has parallels with some anxiety disorders.[17] A 2022 structured study of prominent researchers resulted in the creation of the consensus definition of misophonia, determining that misophonia should be classified as a disorder, and not a symptom of another condition or syndrome.[8] During the early phase of research on misophonia, it was defined by different criteria with variable methods used to diagnose and assess symptom severity. As a result of lack of consensus about how to define and evaluate misophonia, comparisons between study cohorts were difficult, measurement tools were not psychometrically well-validated, and the field could not rigorously assess the efficacy of different treatment approaches. The creation of the definition serves as the foundation of future diagnostic criteria and validated diagnostic tools, and brings cohesion to the diverse and interdisciplinary misophonia research and clinical communities.[8]

Measures

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Misophonia has generally been measured using adult self-report questionnaires.[83] A 2021 review of misophonia and hyperacusis measures found only three misophonia instruments with reported psychometric properties, all of which were adult self-report measures; the review called the evidence regarding the measures' psychometrics "limited".[83] Psychometric properties of a number of additional adult self-report misophonia measures have since been reported in the scholarly literature.[44][45][84][85][86][87][88] Further unvalidated misophonia questionnaires are available on the internet.[18][19][89]

More recently, self-report and caregiver proxy-report measures intended to measure misophonia in children and youth have begun to appear in the scholarly literature.[90][91][92] At least one study uses interviews with caregivers, and sometimes their children, to assess misophonia in children and adolescents.[93]

Another relatively novel development in misophonia assessment is a psychoacoustic measure, which uses adults' self-reported ratings of the pleasantness of sounds to identify a set of sounds that appear to distinguish between people with and without misophonia.[94]

Despite some early proposals,[14][95] there is no scholarly consensus about diagnostic criteria or assessment procedures for misophonia.[8] Due to the difficulty of distinguishing it from other conditions, it is unclear whether any single tool can diagnose misophonia.[18] Academic commentaries make various recommendations, including that misophonia diagnoses be made by multidisciplinary groups and draw upon multiple sources of data, such as patient case histories, interviews, audiological examination, and self-report tools.[18][19][96]

Management

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Health care providers generally try to help people cope with misophonia by recognizing what the person is experiencing and working on coping strategies.[48] A majority of smaller studies done on the subject have focused on the use of tinnitus retraining therapy, cognitive behavioral therapy and exposure therapy, which is believed to decrease the person's awareness of their trigger sounds.[6] These treatment approaches have not been sufficiently studied to determine their effectiveness.[6][36] Other possible treatment options have been theorized by researchers, including acceptance-based approaches and mindfulness.[6] Ultimately, it is speculated that treatment methods may vary significantly in effectiveness from patient to patient.[6]

Minimal research has been conducted on the possible effects of neuromodulation and pharmacologic treatments. A study published in 2022 suggests that some forms of misophonia treatment may vary in effectiveness based on the preference of each patient, particularly in cases of parents with children who have misophonia.[97] In addition, the use of propranolol has also been found to be helpful in some patients.[98]

Clomipramine has anecdotally been found to be of use in at least a certain subset of people suffering from disorders allied with hyperacusis;[99] given its success in the treatment of obsessive-compulsive disorder, it may have a place in the treatment of misophonia,[100] which appears to have parallels with both conditions. Clomipramine does appear to have a distinct potential mediating effect on auditory-tone processing.[101][102] One specific phenomenon observed to this end with clomipramine in at least one instance is reduced electrodermal reactivity to innocuous auditory stimuli.[103]

Whether pindolol (a beta-blocker with similar action to propranolol and augmentative therapeutic effects in obsessive-compulsive disorder[104]) and certain selective serotonin reuptake inhibitors (e.g., fluvoxamine, escitalopram, fluoxetine) can also prove effective in the treatment of misophonia likewise remains to be seen.

Large-scale research has not yet been conducted, but observation of coping strategies people with misophonia use has shown some consistent results.[6] People with misophonia often cope by avoiding distressing situations or distracting themselves from such situations,[105] for example by using earplugs or headphones, mimicking trigger sounds, and playing music.[106]

Sequent repatterning therapy

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Image of Sequent Repatterning logo
The SRT process is associated with this logo, registered in 2019

Sequent Repatterning therapy for misophonia (SRT) is based on the idea that emotional responses are learned and consolidated over time, rather than innate, which makes it a form of cognitive behavioral therapy.[107] Development of this therapy began in 2012 when researcher Christopher Pearson applied aspects of hypnotherapy, parts work therapy, and NLP to create a therapy model for misophonia. He presented his work to the International Association of Neuropsychotherapy in 2017 and an article, "Reviewing Misophonia and its Treatment",[108] was published in International Journal of Neuropsychotherapy later that year. Pearson also contributed to the proposals for diagnostic criteria for misophonia, published in Frontiers.[95] Sequent Repatterning practitioners apply these diagnostic steps when assessing potential clients. Sequent Repatterning Therapy is not generally accepted by the clinical community and has not been shown to be an effective therapy for misophonia, which has not been shown to be caused by habituation. Habituation-based therapies often exacerbate symptoms instead of easing them.

Epidemiology

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Research is still being conducted on misophonia's global prevalence, but a 2023 study found its prevalence in the UK to be around 18%.[47] This study has been cited in popular outlets, including BBC,[109] Medscape,[110] and Medical Xpress.[111] Studies of misophonia's global prevalence have found it to be as low as 5% and as high as 20%.[47] Its prevalence and severity seem to be similar across genders.[47] In the U.S., it is estimated that 3% of people are affected by misophonia. But in multiple studies, it was determined misophonia may be underdiagnosed (it is not yet an officially diagnosable condition), as it is correlated with other auditory disruptions; 92% of patients who are hyperaware of sounds also have misophonia.[18] There is evidence that significant numbers of undergraduate students in some psychology and medical-science departments suffer from misophonia.[112] The University of Nottingham conducted a study of misophonia in one sample of undergraduate medical students.[85] In 2017, similar rates were found in one university in China,[113] suggesting that the disorder is not specific to a culture.

It may be the case that people with misophonia are more likely to have high fluid intelligence.[114]

Associated symptoms

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Some people[who?] have sought to relate misophonia to autonomous sensory meridian response, or auto-sensory meridian response (ASMR), a pleasant form of paresthesia, a tingling sensation that typically begins on the scalp and moves down the back of the neck and upper spine.[115] ASMR is described as the opposite of what can be observed in reactions to specific audio stimuli in misophonia.[116] There are plentiful anecdotal reports of people who claim to have both misophonia and ASMR. Common to these reports is the experience of ASMR in response to some sounds and misophonia in response to others.[116][117][118]

Society and culture

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People who experience misophonia have formed online support groups.[119][14]

In 2016, a documentary about the condition, Quiet Please, was released.[120]

In 2020, a team of misophonia researchers[14] received the Ig Nobel Prize in medicine "for diagnosing a long-unrecognized medical condition".[121]

The 2022 film Tár depicts a conductor with misophonia.[122]

Season 1, episode 4 of Hulu's The Old Man has a brief discussion of misophonia.[123]

Notable cases

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This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources.

See also

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References

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  1. ^ Sanchez TG, Silva FE (2017). "Familial misophonia or selective sound sensitivity syndrome : evidence for autosomal dominant inheritance?". Brazilian Journal of Otorhinolaryngology. 84 (5): 553–559. doi:10.1016/j.bjorl.2017.06.014. PMC 9452240. PMID 28823694.
  2. ^ a b c d Möllmann A, Heinrichs N, Illies L, Potthast N, Kley H (28 March 2023). "The central role of symptom severity and associated characteristics for functional impairment in misophonia". Frontiers in Psychiatry. 14: 1112472. doi:10.3389/fpsyt.2023.1112472. PMC 10086372. PMID 37056403.
  3. ^ a b Norena A (14 February 2024). "Did Kant suffer from misophonia?". Frontiers in Psychology. 15. doi:10.3389/fpsyg.2024.1242516. ISSN 1664-1078. PMC 10899398. PMID 38420172.
  4. ^ a b c d e f g h Palumbo DB, Alsalman O, De Ridder D, Song JJ, Vanneste S (29 June 2018). "Misophonia and Potential Underlying Mechanisms: A Perspective". Frontiers in Psychology. 9: 953. doi:10.3389/fpsyg.2018.00953. PMC 6034066. PMID 30008683.
  5. ^ Bruxner G (April 2016). "'Mastication rage': a review of misophonia - an under-recognised symptom of psychiatric relevance?". Australasian Psychiatry. 24 (2): 195–197. doi:10.1177/1039856215613010. PMID 26508801. S2CID 7106232.
  6. ^ a b c d e f g h Cavanna AE, Seri S (August 2015). "Misophonia: current perspectives". Neuropsychiatric Disease and Treatment. 11: 2117–2123. doi:10.2147/NDT.S81438. PMC 4547634. PMID 26316758.
  7. ^ a b c d e f g h i j k l m n Potgieter I, MacDonald C, Partridge L, Cima R, Sheldrake J, Hoare DJ (July 2019). "Misophonia: A scoping review of research". Journal of Clinical Psychology. 75 (7): 1203–1218. doi:10.1002/jclp.22771. PMID 30859581.
  8. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab Swedo SE, Baguley DM, Denys D, Dixon LJ, Erfanian M, Fioretti A, et al. (2022). "Consensus Definition of Misophonia: A Delphi Study". Frontiers in Neuroscience. 16: 841816. doi:10.3389/fnins.2022.841816. PMC 8969743. PMID 35368272.
  9. ^ a b c d Neacsiu AD, Szymkiewicz V, Galla JT, Li B, Kulkarni Y, Spector CW (25 July 2022). "The neurobiology of misophonia and implications for novel, neuroscience-driven interventions". Frontiers in Neuroscience. 16: 893903. doi:10.3389/fnins.2022.893903. PMC 9359080. PMID 35958984.
  10. ^ Jager I, Vulink N, van Loon A, van der Pol M, Schröder A, Slaghekke S, et al. (28 June 2022). "Synopsis and Qualitative Evaluation of a Treatment Protocol to Guide Systemic Group-Cognitive Behavioral Therapy for Misophonia". Frontiers in Psychiatry. 13: 794343. doi:10.3389/fpsyt.2022.794343. PMC 9275669. PMID 35836662.
  11. ^ a b c Rosenthal MZ, Shan Y, Trumbull J (1 September 2023). "Treatment of Misophonia". Advances in Psychiatry and Behavioral Health. 3 (1): 33–41. doi:10.1016/j.ypsc.2023.03.009.
  12. ^ a b c Mattson SA, D'Souza J, Wojcik KD, Guzick AG, Goodman WK, Storch EA (1 July 2023). "A systematic review of treatments for misophonia". Personalized Medicine in Psychiatry. 39–40: 100104. doi:10.1016/j.pmip.2023.100104. PMC 10276561. PMID 37333720.
  13. ^ a b c Jastreboff MM, Jastreboff PJ (2001). "Components of decreased sound tolerance: hyperacusis, misophonia, phonophobia" (PDF). ITHS News: 5–7. Archived (PDF) from the original on 16 February 2023.
  14. ^ a b c d e f Schröder A, Vulink N, Denys D (23 January 2013). "Misophonia: diagnostic criteria for a new psychiatric disorder". PLOS ONE. 8 (1): e54706. Bibcode:2013PLoSO...854706S. doi:10.1371/journal.pone.0054706. PMC 3553052. PMID 23372758.
  15. ^ a b Brout JJ, Edelstein M, Erfanian M, Mannino M, Miller LJ, Rouw R, et al. (2018). "Investigating Misophonia: A Review of the Empirical Literature, Clinical Implications, and a Research Agenda". Frontiers in Neuroscience. 12: 36. doi:10.3389/fnins.2018.00036. PMC 5808324. PMID 29467604.
  16. ^ a b Taylor S (June 2017). "Misophonia: A new mental disorder?". Medical Hypotheses. 103: 109–117. doi:10.1016/j.mehy.2017.05.003. PMID 28571795.
  17. ^ a b c Brout JJ, Edelstein M, Erfanian M, Mannino M, Miller LJ, Rouw R, et al. (2018). "Investigating Misophonia: A Review of the Empirical Literature, Clinical Implications, and a Research Agenda". Frontiers in Neuroscience. 12: 36. doi:10.3389/fnins.2018.00036. PMC 5808324. PMID 29467604.
  18. ^ a b c d e f g h i j k l m n Ferrer-Torres A, Giménez-Llort L (June 2022). "Misophonia: A Systematic Review of Current and Future Trends in This Emerging Clinical Field". International Journal of Environmental Research and Public Health. 19 (11): 6790. doi:10.3390/ijerph19116790. PMC 9180704. PMID 35682372.
  19. ^ a b c d Henry JA, Theodoroff SM, Edmonds C, Martinez I, Myers PJ, Zaugg TL, et al. (September 2022). "Sound Tolerance Conditions (Hyperacusis, Misophonia, Noise Sensitivity, and Phonophobia): Definitions and Clinical Management". American Journal of Audiology. 31 (3): 513–527. doi:10.1044/2022_AJA-22-00035. PMID 35858241.
  20. ^ Berger JI, Gander PE, Kumar S (August 2024). "A social cognition perspective on misophonia". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 379 (1908): 20230257. doi:10.1098/rstb.2023.0257. PMC 11444241. PMID 39005025.
  21. ^ Jacquemin L, Schecklmann M, Baguley DM (2024). "Hypersensitivity to Sounds". In Schlee W, Langguth B, De Ridder D, Vanneste S, Kleinjung T, Møller AR (eds.). Textbook of Tinnitus. Cham: Springer International Publishing. pp. 25–34. doi:10.1007/978-3-031-35647-6_3. ISBN 978-3-031-35647-6.
  22. ^ Jastreboff PJ (2024). "The Neurophysiological Model of Tinnitus and Decreased Sound Tolerance". In Schlee W, Langguth B, De Ridder D, Vanneste S (eds.). Textbook of Tinnitus. Cham: Springer International Publishing. pp. 231–249. doi:10.1007/978-3-031-35647-6_20. ISBN 978-3-031-35647-6.
  23. ^ a b c Jaswal SM, De Bleser AK, Handy TC (August 2021). "Misokinesia is a sensitivity to seeing others fidget that is prevalent in the general population". Scientific Reports. 11 (1): 17204. Bibcode:2021NatSR..1117204J. doi:10.1038/s41598-021-96430-4. PMC 8390668. PMID 34446737.
  24. ^ a b Holohan D, Marfilius K, Smith CJ (September 2023). "Misophonia: A Review of the Literature and Its Implications for the Social Work Profession". Social Work. 68 (4): 341–348. doi:10.1093/sw/swad029. PMID 37463856.
  25. ^ Sharp D (2 July 2024). "For Whom the Bell Tolls: Misophonia as a complex experience of hope and dread in self-with-other regulation". Psychoanalysis, Self and Context. 19 (3): 354–369. doi:10.1080/24720038.2024.2332240. ISSN 2472-0038.
  26. ^ a b c Guzick AG, Rast CE, Maddox BB, Rodriguez Barajas S, Clinger J, McGuire J, et al. (October 2024). ""How Can I Get Out of This?": A Qualitative Study of the Phenomenology and Functional Impact of Misophonia in Youth and Families". Psychopathology: 1–11. doi:10.1159/000535044. PMID 39369709.
  27. ^ Aron W (9 September 2013). "Going to School with Misophonia: Some schooling on a rare disorder". Psychology Today. Retrieved 10 November 2024.
  28. ^ "Misophonia at School: Disability Accommodations". SoQuiet. Retrieved 10 November 2024.
  29. ^ Gowda V, Prabhu P (October 2024). "Prevalence of Misophonia in Adolescents and Adults Across the Globe: A Systematic Review". Indian Journal of Otolaryngology and Head and Neck Surgery. 76 (5): 4614–4622. doi:10.1007/s12070-024-04946-8. PMC 11456068. PMID 39376325.
  30. ^ Dixon LJ, Schadegg MJ, Clark HL, Sevier CJ, Witcraft SM (July 2024). "Prevalence, phenomenology, and impact of misophonia in a nationally representative sample of U.S. adults". Journal of Psychopathology and Clinical Science. 133 (5): 403–412. doi:10.1037/abn0000904. PMID 38780601.
  31. ^ Jakubovski E, Müller A, Kley H, de Zwaan M, Müller-Vahl K (21 November 2022). "Prevalence and clinical correlates of misophonia symptoms in the general population of Germany". Frontiers in Psychiatry. 13: 1012424. doi:10.3389/fpsyt.2022.1012424. PMC 9720274. PMID 36479555.
  32. ^ Kılıç C, Öz G, Avanoğlu KB, Aksoy S (August 2021). "The prevalence and characteristics of misophonia in Ankara, Turkey: population-based study". BJPsych Open. 7 (5): e144. doi:10.1192/bjo.2021.978. PMC 8358974. PMID 34353403.
  33. ^ "Misophonia". Tinnitus & Hyperacusis Center. Archived from the original on 22 January 2023. Retrieved 8 October 2022.
  34. ^ de Freytas-Tamura K (3 February 2017). "Misophonia Sufferers: Scientists May Have Found the Root of Your Pain". The New York Times. Archived from the original on 25 November 2022. Retrieved 6 October 2022.
  35. ^ Jastreboff MM, Jastreboff PJ (18 June 2001). "Hyperacusis". AudiologyOnline. Archived from the original on 22 February 2023. Retrieved 8 October 2022.
  36. ^ a b Cavanna AE (April 2014). "What is misophonia and how can we treat it?". Expert Review of Neurotherapeutics. 14 (4): 357–359. doi:10.1586/14737175.2014.892418. PMID 24552574. S2CID 36026220.
  37. ^ Jastreboff MM, Jastreboff PJ (November 2002). "Decreased Sound Tolerance and Tinnitus Retraining Therapy (TRT)". Australian and New Zealand Journal of Audiology. 24 (2): 74–84. doi:10.1375/audi.24.2.74.31105. Archived from the original on 19 March 2023.
  38. ^ a b c Dozier T, Mitchell N (4 October 2023). "Novel five-phase model for understanding the nature of misophonia, a conditioned aversive reflex disorder". F1000Research. 12: 808. doi:10.12688/f1000research.133506.3. PMC 10594049. PMID 37881332.
  39. ^ Moyer MW (9 September 2022). "When You Can't Stand the Sound of Chewing (or Crunching, or Sniffling)". The New York Times. ISSN 0362-4331. Retrieved 9 November 2024.
  40. ^ Dresden D (10 November 2023). "Misophonia: What it is, symptoms, and triggers". Medical News Today. Retrieved 9 November 2024.
  41. ^ Blackwelder C (21 August 2024). "'Little House on the Prairie' alum Melissa Gilbert details life with misophonia". ABC News. Retrieved 9 November 2024.
  42. ^ Cohen J (17 June 2016). "Misophonia: When a crunch, chew, or a sniffle triggers hot rage". Stat News. Retrieved 9 November 2024.
  43. ^ "Understanding Misophonia". Misophonia Research Fund. Misophonia Research Fund. Retrieved 9 November 2024.
  44. ^ a b Rosenthal MZ, Anand D, Cassiello-Robbins C, Williams ZJ, Guetta RE, Trumbull J, et al. (29 September 2021). "Development and Initial Validation of the Duke Misophonia Questionnaire". Frontiers in Psychology. 12: 709928. doi:10.3389/fpsyg.2021.709928. PMC 8511674. PMID 34659024.
  45. ^ a b Vitoratou S, Uglik-Marucha N, Hayes C, Gregory J (28 October 2021). "Listening to People with Misophonia: Exploring the Multiple Dimensions of Sound Intolerance Using a New Psychometric Tool, the S-Five, in a Large Sample of Individuals Identifying with the Condition". Psych. 3 (4): 639–662. doi:10.3390/psych3040041. ISSN 2624-8611.
  46. ^ Vitoratou S (4 January 2023). "Misophonia in the UK: Prevalence and Norms for the S-Five in a UK Representative Sample, 2020-2022". [Data Collection]. Colchester, Essex: UK Data Service. doi:10.5255/UKDA-SN-856149.
  47. ^ a b c d Vitoratou S, Hayes C, Uglik-Marucha N, Pearson O, Graham T, Gregory J (22 March 2023). "Misophonia in the UK: Prevalence and norms from the S-Five in a UK representative sample". PLOS ONE. 18 (3): e0282777. Bibcode:2023PLoSO..1882777V. doi:10.1371/journal.pone.0282777. PMC 10032546. PMID 36947525.
  48. ^ a b c d e Duddy DF, Oeding KA (2014). "Misophonia: An Overview". Semin Hear. 35 (2): 084–091. doi:10.1055/s-0034-1372525. S2CID 76090599.
  49. ^ Simner J, Rinaldi LJ (1 December 2023). "Misophonia, self-harm and suicidal ideation". Psychiatry and Clinical Neurosciences Reports. 2 (4): e142. doi:10.1002/pcn5.142. ISSN 2769-2558. PMC 11114359. PMID 38868724.
  50. ^ Alekri J, Al Saif F (3 April 2019). "Suicidal misophonia: a case report". Psychiatry and Clinical Psychopharmacology. 29 (2): 232–237. doi:10.1080/24750573.2019.1597585. ISSN 2475-0573.
  51. ^ Muñoz K, Woolley MG, Velasquez D, Ortiz D, San Miguel GG, Petersen JM, et al. (30 September 2024). "Audiological Characteristics of a Sample of Adults With Misophonia". American Journal of Audiology. 33 (4): 1202–1211. doi:10.1044/2024_AJA-24-00111. ISSN 1059-0889. PMID 39348505.
  52. ^ Suraj U, Nisha KV, Prabhu P (1 April 2024). "Normal linear and non-linear cochlear mechanisms and efferent system functioning in individuals with misophonia". European Archives of Oto-Rhino-Laryngology. 281 (4): 1709–1716. doi:10.1007/s00405-023-08273-6. ISSN 0937-4477. PMID 37837477.
  53. ^ Williams ZJ (21 June 2024), Investigating the Nature of Decreased Sound Tolerance in Autistic and Non-autistic Adults, Neuroscience, Nashville, TN, USA: Vanderbilt University, pp. 197–249
  54. ^ a b c d Jastreboff P, Jastreboff M (29 April 2014). "Treatments for Decreased Sound Tolerance (Hyperacusis and Misophonia)". Seminars in Hearing. 35 (2): 105–120. doi:10.1055/s-0034-1372527. ISSN 0734-0451.
  55. ^ a b c d e f g Jastreboff PJ, Jastreboff MM (23 March 2023). "The neurophysiological approach to misophonia: Theory and treatment". Frontiers in Neuroscience. 17. doi:10.3389/fnins.2023.895574. ISSN 1662-453X. PMC 10076672. PMID 37034168.
  56. ^ Salvi R, Chen GD, Manohar S (1 December 2022). "Hyperacusis: Loudness intolerance, fear, annoyance and pain". Hearing Research. 426: 108648. doi:10.1016/j.heares.2022.108648. PMID 36395696.
  57. ^ a b c d Jastreboff PJ (2024), Schlee W, Langguth B, De Ridder D, Vanneste S (eds.), "The Neurophysiological Model of Tinnitus and Decreased Sound Tolerance", Textbook of Tinnitus, Cham: Springer International Publishing, pp. 231–249, doi:10.1007/978-3-031-35647-6_20, ISBN 978-3-031-35647-6, retrieved 4 November 2024
  58. ^ a b c d e f g h i j k l m n Berger JI, Gander PE, Kumar S (26 August 2024). "A social cognition perspective on misophonia". Philosophical Transactions of the Royal Society B: Biological Sciences. 379 (1908). doi:10.1098/rstb.2023.0257. ISSN 0962-8436. PMC 11444241. PMID 39005025.
  59. ^ a b c Kumar S, Dheerendra P, Erfanian M, Benzaquén E, Sedley W, Gander PE, et al. (June 2021). "The Motor Basis for Misophonia". The Journal of Neuroscience. 41 (26): 5762–5770. doi:10.1523/JNEUROSCI.0261-21.2021. PMC 8244967. PMID 34021042.
  60. ^ a b Williams ZJ (21 June 2024), Investigating the Nature of Decreased Sound Tolerance in Autistic and Non-autistic Adults, Neuroscience, Nashville, TN, USA: Vanderbilt University
  61. ^ Borsboom D, van der Maas HL, Dalege J, Kievit RA, Haig BD (1 July 2021). "Theory Construction Methodology: A Practical Framework for Building Theories in Psychology". Perspectives on Psychological Science. 16 (4): 756–766. doi:10.1177/1745691620969647. ISSN 1745-6916. PMID 33593167.
  62. ^ Robinaugh DJ, Haslbeck JM, Ryan O, Fried EI, Waldorp LJ (1 July 2021). "Invisible Hands and Fine Calipers: A Call to Use Formal Theory as a Toolkit for Theory Construction". Perspectives on Psychological Science. 16 (4): 725–743. doi:10.1177/1745691620974697. ISSN 1745-6916. PMC 8273080. PMID 33593176.
  63. ^ Kumar S, Tansley-Hancock O, Sedley W, Winston JS, Callaghan MF, Allen M, et al. (February 2017). "The Brain Basis for Misophonia". Current Biology. 27 (4): 527–533. Bibcode:2017CBio...27..527K. doi:10.1016/j.cub.2016.12.048. PMC 5321671. PMID 28162895.
  64. ^ Samermit P, Young M, Allen AK, Trillo H, Shankar S, Klein A, et al. (22 July 2022). "Development and Evaluation of a Sound-Swapped Video Database for Misophonia". Frontiers in Psychology. 13. doi:10.3389/fpsyg.2022.890829. ISSN 1664-1078. PMC 9355709. PMID 35936325.
  65. ^ Savard MA, Sares AG, Coffey EB, Deroche ML (26 May 2022). "Specificity of Affective Responses in Misophonia Depends on Trigger Identification". Frontiers in Neuroscience. 16. doi:10.3389/fnins.2022.879583. ISSN 1662-453X. PMC 9179422. PMID 35692416.
  66. ^ a b Ash PA, Benzaquén E, Gander PE, Berger JI, Kumar S (1 January 2024). "Mimicry in misophonia: A large-scale survey of prevalence and relationship with trigger sounds". Journal of Clinical Psychology. 80 (1): 186–197. doi:10.1002/jclp.23605. ISSN 0021-9762. PMID 37850971.
  67. ^ Campbell ME, Mehrkanoon S, Cunnington R (1 March 2018). "Intentionally not imitating: Insula cortex engaged for top-down control of action mirroring". Neuropsychologia. 111: 241–251. doi:10.1016/j.neuropsychologia.2018.01.037. PMID 29408525.
  68. ^ Williams ZJ, He JL, Cascio CJ, Woynaroski TG (February 2021). "A review of decreased sound tolerance in autism: Definitions, phenomenology, and potential mechanisms". Neuroscience & Biobehavioral Reviews. 121: 1–17. doi:10.1016/j.neubiorev.2020.11.030. PMC 7855558. PMID 33285160.
  69. ^ Jastreboff PJ, Jastreboff MM (2015). "Decreased sound tolerance". In Aminoff MJ, Boller F, Swaab DF (eds.). The Human Auditory System - Fundamental Organization and Clinical Disorders. Handbook of Clinical Neurology. Vol. 129. Elsevier. pp. 375–87. doi:10.1016/B978-0-444-62630-1.00021-4. ISBN 978-0-444-62630-1. PMID 25726280.
  70. ^ Smit DJ, Bakker M, Abdellaoui A, Hoetink AE, Vulink NC, Denys D (9 September 2022). "Genetic evidence for the link of misophonia with psychiatric disorders and personality". medRxiv 10.1101/2022.09.04.22279567.
  71. ^ Zai G, Dembo J, Levitsky N, Richter MA (September 2022). "Misophonia: A Detailed Case Series and Literature Review". The Primary Care Companion for CNS Disorders. 24 (5). doi:10.4088/PCC.21cr03124. PMID 36179361. S2CID 252645598.
  72. ^ Storch EA, Mckay D, Abramowitz JS, eds. (2019). Advanced Casebook of Obsessive-Compulsive and Related Disorders: Conceptualizations and Treatment. Academic Press. ISBN 978-0-12-816557-7.[page needed]
  73. ^ Webber TA, Johnson PL, Storch EA (March 2014). "Pediatric misophonia with comorbid obsessive-compulsive spectrum disorders". General Hospital Psychiatry. 36 (2): 231.e1–231.e2. doi:10.1016/j.genhosppsych.2013.10.018. PMID 24333158.
  74. ^ Guzick AG, Cervin M, Smith EE, Clinger J, Draper I, Goodman WK, et al. (March 2023). "Clinical characteristics, impairment, and psychiatric morbidity in 102 youth with misophonia". Journal of Affective Disorders. 324: 395–402. doi:10.1016/j.jad.2022.12.083. PMC 9878468. PMID 36584703.
  75. ^ Cassiello-Robbins C, Anand D, McMahon K, Brout J, Kelley L, Rosenthal MZ (2021). "A Preliminary Investigation of the Association Between Misophonia and Symptoms of Psychopathology and Personality Disorders". Frontiers in Psychology. 11: 519681. doi:10.3389/fpsyg.2020.519681. PMC 7840505. PMID 33519567.
  76. ^ Edelstein M, Brang D, Rouw R, Ramachandran VS (2013). "Misophonia: physiological investigations and case descriptions". Frontiers in Human Neuroscience. 7: 296. doi:10.3389/fnhum.2013.00296. PMC 3691507. PMID 23805089.
  77. ^ Brout JJ, Edelstein M, Erfanian M, Mannino M, Miller LJ, Rouw R, et al. (7 February 2018). "Investigating Misophonia: A Review of the Empirical Literature, Clinical Implications, and a Research Agenda". Frontiers in Neuroscience. 12: 36. doi:10.3389/fnins.2018.00036. PMC 5808324. PMID 29467604.
  78. ^ Holtz Z, Rosenthal MZ, Trumbull J (2023). "Disentangling the Relationship between Misophonia, Anxiety, and Obsessive-Compulsive Personality Disorder". SSRN 4356614.
  79. ^ Szykowny N (2020). The Relationship Between Misophonia and Perfectionism (Doctor of Psychology thesis). Palo Alto University.[page needed]
  80. ^ Castro A, Lindberg RR, Kim G, Brennan C, Jain N, Khan RA, et al. (10 March 2023). "Obsessive-Compulsive Symptoms and Sound Sensitivities: Comparing Misophonia and Hyperacusis". PsyArXiv Preprints. doi:10.31234/osf.io/92yas.
  81. ^ Wu MS, Banneyer KN (2020). "Chew on this: Considering misophonia and obsessive-compulsive disorder". Advanced Casebook of Obsessive-Compulsive and Related Disorders. Academic Press. pp. 1–19. doi:10.1016/B978-0-12-816563-8.00001-2. ISBN 978-0-12-816563-8. S2CID 213436071.
  82. ^ Reid AM, Guzick AG, Gernand A, Olsen B (July 2016). "Intensive cognitive-behavioral therapy for comorbid misophonic and obsessive-compulsive symptoms: A systematic case study". Journal of Obsessive-Compulsive and Related Disorders. 10: 1–9. doi:10.1016/j.jocrd.2016.04.009.
  83. ^ a b Kula, F. B., Cropley, M., Aazh, H. (July 2022). "Hyperacusis and Misophonia: A Systematic Review of Psychometric Measures". Journal of the American Academy of Audiology. 33 (7/08): 417–428. doi:10.1055/a-1896-5032. ISSN 2157-3107. PMID 35817311.
  84. ^ Dibb, B., Golding, S. E., Dozier, T. H. (2021). "The development and validation of the Misophonia response scale". Journal of Psychosomatic Research. 149. Elsevier Inc.: 110587. doi:10.1016/j.jpsychores.2021.110587. ISSN 0022-3999. PMID 34390941.
  85. ^ a b Naylor J, Caimino C, Scutt P, Hoare DJ, Baguley DM (June 2021). "The Prevalence and Severity of Misophonia in a UK Undergraduate Medical Student Population and Validation of the Amsterdam Misophonia Scale". The Psychiatric Quarterly. 92 (2): 609–619. doi:10.1007/s11126-020-09825-3. PMC 8110492. PMID 32829440.
  86. ^ Remmert, N., Schmidt, K. M. B., Mussel, P., Hagel, M. L., Eid, M. (21 June 2022). "The Berlin Misophonia Questionnaire Revised (BMQ-R): Development and validation of a symptom-oriented diagnostical instrument for the measurement of misophonia". PLOS ONE. 17 (6): e0269428. Bibcode:2022PLoSO..1769428R. doi:10.1371/journal.pone.0269428. ISSN 1932-6203. PMC 9212156. PMID 35727794.
  87. ^ Simner, J., Rinaldi, L. J., Ward, J. (27 February 2024). "An Automated Online Measure for Misophonia: The Sussex Misophonia Scale for Adults". Assessment. 31 (8): 1598–1614. doi:10.1177/10731911241234104. ISSN 1552-3489. PMC 11528938. PMID 38414185.
  88. ^ Williams, Z. J., Cascio, C. J., Woynaroski, T. G. (22 July 2022). "Psychometric validation of a brief self-report measure of misophonia symptoms and functional impairment: The duke-vanderbilt misophonia screening questionnaire". Frontiers in Psychology. 13: 897901. doi:10.3389/fpsyg.2022.897901. ISSN 1664-1078. PMC 9355318. PMID 35936331.
  89. ^ Siepsiak, M., Sliwerski, A., Dragan, W. Ł. (2020). "Development and psychometric properties of MisoQuest — A new self-report questionnaire for misophonia". International Journal of Environmental Research and Public Health. 17 (5): 1797. doi:10.3390/ijerph17051797. PMC 7084437. PMID 32164250.
  90. ^ Cervin, M., Guzick, A. G., Clinger, J., Smith, E. E. A., Draper, I. A., Goodman, W. K., et al. (May 2023). "Measuring misophonia in youth: A psychometric evaluation of child and parent measures". Journal of Affective Disorders. 39: 180–186. doi:10.1016/j.jad.2023.05.093. ISSN 0165-0327. PMC 11165319. PMID 37263358.
  91. ^ Rappoldt, L. R., Kan, K. J., Dalmeijer, L., Rutten, S. A., Van Horen, R., Van Der Pol, M. M., et al. (14 November 2024). "Psychometric Validation of the New Misophonia Screening List—Child and Youth and AMISOS-Y (Dutch Child- and Parent-Report Versions) for Assessing Misophonia in Youth". Child Psychiatry & Human Development. doi:10.1007/s10578-024-01781-4. ISSN 1573-3327. PMID 39540976.
  92. ^ Rinaldi, L. J., Smees, R., Ward, J., Simner, J. (6 April 2022). "Poorer Well-Being in Children With Misophonia: Evidence From the Sussex Misophonia Scale for Adolescents". Frontiers in Psychology. 13: 808379. doi:10.3389/fpsyg.2022.808379. ISSN 1664-1078. PMC 9019493. PMID 35465571.
  93. ^ Siepsiak, M., Turek, A., Michałowska, M., Gambin, M., Dragan, W. Ł. (8 September 2023). "Misophonia in Children and Adolescents: Age Differences, Risk Factors, Psychiatric and Psychological Correlates. A Pilot Study with Mothers' Involvement". Child Psychiatry & Human Development. doi:10.1007/s10578-023-01593-y. ISSN 1573-3327 0009-398X, 1573-3327. PMID 37684420. Retrieved 12 September 2023. {{cite journal}}: Check |issn= value (help)
  94. ^ Enzler, F., Loriot, C., Fournier, P., Noreña, A. J. (2021). "A psychoacoustic test for misophonia assessment". Scientific Reports. 11 (1): 11044. Bibcode:2021NatSR..1111044E. doi:10.1038/s41598-021-90355-8. ISSN 2045-2322. PMC 8155015. PMID 34040061.
  95. ^ a b Dozier TH, Lopez M, Pearson C (14 November 2017). "Proposed Diagnostic Criteria for Misophonia: A Multisensory Conditioned Aversive Reflex Disorder". Frontiers in Psychology. 8: 1975. doi:10.3389/fpsyg.2017.01975. PMC 5694628. PMID 29184520.
  96. ^ Campbell, J. (10 July 2023). "Misophonia: A Need for audiologic diagnostic guidelines". Journal of the American Academy of Audiology. 34 (7–08): a-2125-7645. doi:10.1055/a-2125-7645. ISSN 2157-3107. PMC 11586086. PMID 37429565.
  97. ^ Smith EE, Guzick AG, Draper IA, Clinger J, Schneider SC, Goodman WK, et al. (November 2022). "Perceptions of various treatment approaches for adults and children with misophonia". Journal of Affective Disorders. 316: 76–82. doi:10.1016/j.jad.2022.08.020. PMC 9884516. PMID 35970326.
  98. ^ Webb J (January 2022). "β-Blockers for the Treatment of Misophonia and Misokinesia". Clinical Neuropharmacology. 45 (1): 13–14. doi:10.1097/WNF.0000000000000492. PMID 35029865. S2CID 245932937.
  99. ^ Levine RA, Oron Y (2015). "Tinnitus". The Human Auditory System - Fundamental Organization and Clinical Disorders. Handbook of Clinical Neurology. Vol. 129. Elsevier. pp. 409–431. doi:10.1016/B978-0-444-62630-1.00023-8. ISBN 978-0-444-62630-1. PMID 25726282.
  100. ^ Hocaoglu C (30 March 2018). "A little known topic misophonia: two case reports". Dusunen Adam. 31 (1): 89–96. doi:10.5350/DAJPN2018310109.
  101. ^ Kozak MJ, Rossi M, McCarthy PR, Foa EB (November 1989). "Effects of imipramine on the autonomic responses of obsessive-compulsives to auditory tones". Biological Psychiatry. 26 (7): 707–716. doi:10.1016/0006-3223(89)90105-4. PMID 2804191. S2CID 26076762.
  102. ^ Zahn TP, Insel TR, Murphy DL. Psychophysiological changes during pharmacological treatment of patients with obsessive compulsive disorder. Br J Psychiatry. 1984 Jul;145:39-44. doi: 10.1192/bjp.145.1.39. PMID 6378303.
  103. ^ Zahn TP, Insel TR, Murphy DL (July 1984). "Psychophysiological changes during pharmacological treatment of patients with obsessive compulsive disorder". The British Journal of Psychiatry. 145 (1): 39–44. doi:10.1192/bjp.145.1.39. PMID 6378303.
  104. ^ Dannon PN, Sasson Y, Hirschmann S, Iancu I, Grunhaus LJ, Zohar J (May 2000). "Pindolol augmentation in treatment-resistant obsessive compulsive disorder: a double-blind placebo controlled trial". European Neuropsychopharmacology. 10 (3): 165–169. doi:10.1016/S0924-977X(00)00065-1. PMID 10793318. S2CID 28452756.
  105. ^ Cavanna AE, Seri S (August 2015). "Misophonia: current perspectives". Neuropsychiatric Disease and Treatment. 11: 2117–2123. doi:10.2147/NDT.S81438. PMC 4547634. PMID 26316758.
  106. ^ Edelstein M, Brang D, Rouw R, Ramachandran VS (June 2013). "Misophonia: physiological investigations and case descriptions". Frontiers in Human Neuroscience. 7: 296. doi:10.3389/fnhum.2013.00296. PMC 3691507. PMID 23805089.
  107. ^ "Quick facts, Diagnosis, Causes & Treatment | Misophonia Treatment". Retrieved 29 August 2023.
  108. ^ Pearson C (2017). "Reviewing Misophonia and its Treatment". International Journal of Neuropsychotherapy. 5 (1): 2–10. doi:10.12744/ijnpt.2017.1.0002-0010 (inactive 10 November 2024).{{cite journal}}: CS1 maint: DOI inactive as of November 2024 (link)
  109. ^ "What sounds drive you crazy?". BBC Newsround. 23 March 2023. Retrieved 14 June 2023.
  110. ^ "About a Fifth of Us Are Hypersensitive to Sounds". Medscape. Retrieved 14 June 2023.
  111. ^ Public Library of Science. "Nearly 1 in 5 UK adults may have misophonia, experiencing significant negative responses to sounds". medicalxpress.com. Retrieved 14 June 2023.
  112. ^ Yektatalab S, Mohammadi A, Zarshenas L (October 2022). "The Prevalence of Misophonia and Its Relationship with Obsessive-compulsive Disorder, Anxiety, and Depression in Undergraduate Students of Shiraz University of Medical Sciences: A Cross-Sectional Study". International Journal of Community Based Nursing and Midwifery. 10 (4): 259–268. doi:10.30476/IJCBNM.2022.92902.1888. PMC 9579453. PMID 36274664.
  113. ^ Zhou X, Wu MS, Storch EA (July 2017). "Misophonia symptoms among Chinese university students: Incidence, associated impairment, and clinical correlates". Journal of Obsessive-Compulsive and Related Disorders. 14: 7–12. doi:10.1016/j.jocrd.2017.05.001.
  114. ^ Watson L (2022). Investigation of a Misophonia and Fluid Intelligence Relationship: Sound Spectrum Variation Impact on Fluid Intelligence Task Responses (Thesis). doi:10.58809/MYID1761.[page needed]
  115. ^ Mahady A, Takac M, De Foe A (March 2023). "What is autonomous sensory meridian response (ASMR)? A narrative review and comparative analysis of related phenomena". Consciousness and Cognition. 109: 103477. doi:10.1016/j.concog.2023.103477. PMID 36806854. S2CID 256874981.
  116. ^ a b Rouw R, Erfanian M (March 2018). "A Large-Scale Study of Misophonia". Journal of Clinical Psychology. 74 (3): 453–479. doi:10.1002/jclp.22500. hdl:11245.1/c9c45e84-3c70-407e-aa2f-782ccdb79791. PMID 28561277.
  117. ^ "ASMR and Misophonia: Sounds-Crazy!". Science in our world: certainty and controversy. Pennsylvania State University. 16 September 2015. Archived from the original on 30 January 2023.
  118. ^ Higa K (11 June 2015). "Technicalities of the Tingles: The science of sounds that feel good. #ASMR". Neuwrite. Archived from the original on 30 January 2023. Retrieved 20 January 2016.
  119. ^ Cohen J (5 September 2011). "When a Chomp or a Slurp is a Trigger for Outrage". The New York Times. Archived from the original on 20 December 2022. Retrieved 5 February 2012.
  120. ^ Jeffries A (17 June 2016). "There's a New Film About Misophonia, Where People Get Enraged by Certain Sounds". Motherboard. Archived from the original on 1 July 2022. Retrieved 18 September 2020.
  121. ^ "Past Ig Winners". improbable.com. 1 August 2006.
  122. ^ "Cate Blanchett Can't Imagine Her Life Without Lydia Tár". W Magazine. 9 January 2023. Retrieved 14 June 2023.
  123. ^ "The Old Man" IV (TV Episode 2022) - Trivia - IMDb, retrieved 14 June 2023
  124. ^ Blackwelder C (21 August 2024). "'Little House on the Prairie' alum Melissa Gilbert details life with misophonia". Good Morning America. Retrieved 22 August 2024.
  125. ^ "Off the Menu with Ed Gamble and James Acaster".
  126. ^ Lerner BH (2 March 2015). "Please Stop Making That Noise". Well. New York Times. Retrieved 18 October 2016.
  127. ^ "S6E19 - Lisa Loeb | The Misophonia Podcast". S6E19 - Lisa Loeb | The Misophonia Podcast. Retrieved 14 June 2023.
  128. ^ Bisley A (10 March 2015). "Melanie Lynskey on Togetherness, realism and 'radical' nudity". The Guardian. ISSN 0261-3077. Retrieved 30 June 2017.
  129. ^ Allen T (30 March 2016). "10 Things You Never Knew About Laila McQueen". Queerty. Retrieved 31 October 2023.
  130. ^ sourspice (10 October 2024). "Pharrell 🤝 Misophonia". r/misophonia. Retrieved 23 October 2024.
  131. ^ Desborough J (26 July 2018). "Kelly Osbourne reveals strange phobia which causes her to rip food from people's mouths". mirror.co.uk. As the Loose Women panel discussed irritating habits that their husbands might have, she told Jane Moore: "I have misophonia, it's a phobia of mouth noises. I can't handle it." Kelly revealed she can't bear the sound of loud eating, which is a problem for her dating as she as men often have "bigger mouths" than women .. Misophonia is technically a phobia of sounds in general, and is sometime referred to as "sound rage" as people become enraged just by noises which seem to rub them up the wrong way.
  132. ^ Misophonia: Kelly Ripa Has Rare Disorder. 20/20. ABC News. 18 May 2012. Archived from the original on 19 June 2012. Retrieved 18 October 2016.
  133. ^ Dogshit, Comedy and Pain (YouTube video). The Sarah Silverman Podcast. 17 March 2022. Retrieved 8 February 2023.

Further reading

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