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The first sequences of keratins revealed that keratins could be grouped into two categories based on their sequence homologies.[ 1] [ 2] [ 2] intermediate filament proteins.
Keratins in this table are classified in the first two columns according to the nomenclature established in 2006.[ 3]
Human epithelial keratins [ edit ]
Protein name [ 3] Gene name [ 3] Other protein name Other gene name
K9 KRT9 Ka9
K10 KRT10 Ka10
K12 KRT12 Ka12
K13 KRT13 Ka13
K14 KRT14 Ka14
K15 KRT15 Ka15
K16 KRT16 Ka16
K17 KRT17 Ka17
K18 KRT18 Ka18
K19 KRT19 Ka19
K20 KRT20 Ka20
K23 KRT23 Ka23
K24 KRT24 Ka24
K25 KRT25 Ka38, K25irs1, K10C, hIRSa1
KRT25A
K26 KRT26 Ka39, K25irs2, K10D
K27 KRT27 Ka40, K25irs3, K10B, hIRSa3.1
K28 KRT28 Ka41, K25irs4, hIRSa2
Human hair keratins [ edit ] [ edit ]
Protein name [ 3] Gene name [ 3] Other protein name Other gene name
K41 chimp, gorilla, dog[ 4] KRT41 chimp, gorilla, dog; KRT41P man, horseφhHaA, Ka34P man
K42 mouse, ratKRT42 mouse, rat; KRT42P manKa22 mouse, rat, K17n mouse, rat
Human keratin pseudogenes [ edit ] Human epithelial keratin [ edit ]
Protein name [ 3] Gene name [ 3] Other protein name Other gene name
K1 KRT1 Kb1
K2 KRT2 Kb2, K2e
KRT2A
K3 KRT3 Kb3
K4 KRT4 Kb4
K5 KRT5 Kb5
K6a KRT6A Kb6
K6b KRT6B Kb10
K7 KRT7 Kb7
K8 KRT8 Kb8
K71 KRT71 Kb34, K6irs1
K72 KRT72 Kb35, K6irs2
K73 KRT73 Kb36, K6irs3
K74 KRT74 Kb37, K6irs4
K75 KRT75 Kb18, K6hf
K76 KRT76 Kb9, K2p
KRT2B
K77 KRT77 Kb39, K1b
K78 KRT78 Kb40, K5b
K79 KRT79 Kb38, K6I
K80 KRT80 Kb20
Human hair keratins [ edit ]
Protein name [ 3] Gene name [ 3] Other protein name Other gene name
K81 KRT81 Kb21, Hb1, K2.9
KRTHB1
K82 KRT82 Kb22, Hb2
KRTHB2
K83 KRT83 Kb23, Hb3, K2.10
KRTHB3
K84 KRT84 Kb24, Hb4
KRTHB4
K85 KRT85 Kb25, Hb5, K2.12
KRTHB5
K86 KRT86 Kb26, Hb6, K2.11
KRTHB6
Human keratin pseudogenes [ edit ]
^ Hanukoglu, I.; Fuchs, E. (Nov 1982). "The cDNA sequence of a human epidermal keratin: divergence of sequence but conservation of structure among intermediate filament proteins" . Cell . 31 (1): 243–52. doi :10.1016/0092-8674(82)90424-X . PMID 6186381 . S2CID 35796315 . Archived from the original on 2021-01-26. Retrieved 2019-12-11 . ^ a b Hanukoglu, I.; Fuchs, E. (Jul 1983). "The cDNA sequence of a Type II cytoskeletal keratin reveals constant and variable structural domains among keratins" . Cell . 33 (3): 915–24. doi :10.1016/0092-8674(83)90034-X . PMID 6191871 . S2CID 21490380 . Archived from the original on 2021-01-26. Retrieved 2019-09-12 . ^ a b c d e f g h i j k l m n o Schweizer J, Bowden PE, Coulombe PA, et al. (July 2006). "New consensus nomenclature for mammalian keratins" . J. Cell Biol . 174 (2): 169–74. doi :10.1083/jcb.200603161 . PMC 2064177 PMID 16831889 . ^ Balmer, P; Bauer, A; Pujar, S; McGarvey, KM; Welle, M; Galichet, A; Müller, EJ; Pruitt, KD; Leeb, T; Jagannathan, V (2017). "A curated catalog of canine and equine keratin genes" . PLOS ONE . 12 (8): e0180359. Bibcode :2017PLoSO..1280359B . doi :10.1371/journal.pone.0180359 PMC 5573215 PMID 28846680 .
