KIAA0157

ABRAXAS2
Identifiers
Aliases	ABRAXAS2, ABRO1, KIAA0157, FAM175B, family with sequence similarity 175 member B, abraxas 2, BRISC complex subunit
External IDs	OMIM: 611144; MGI: 1926116; HomoloGene: 12970; GeneCards: ABRAXAS2; OMA:ABRAXAS2 - orthologs
Gene location (Human) Chr. Chromosome 10 (human) Band 10q26.13 Start 124,801,819 bp End 124,836,667 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 F3 Start 132,460,954 bp End 132,486,840 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte middle temporal gyrus Skeletal muscle tissue of biceps brachii Brodmann area 23 gonad deltoid muscle gastrocnemius muscle Achilles tendon parietal pleura visceral pleura Top expressed in Paneth cell superior cervical ganglion otolith organ utricle hand ureter foot temporal muscle facial motor nucleus genital tubercle More reference expression data BioGPS n/a
Gene ontology Molecular function microtubule binding polyubiquitin modification-dependent protein binding protein binding Cellular component cytoplasm centrosome spindle pole BRISC complex spindle pole centrosome midbody microtubule cytoskeleton nucleus microtubule minus-end cytosol Biological process chromosome segregation cell division mitotic spindle assembly response to ischemia protein K63-linked deubiquitination cell cycle attachment of spindle microtubules to kinetochore protein deubiquitination mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23172 109359 Ensembl ENSG00000165660 ENSMUSG00000030965 UniProt Q15018 Q3TCJ1 RefSeq (mRNA) NM_032182 NM_198017 RefSeq (protein) NP_115558 NP_932134 Location (UCSC) Chr 10: 124.8 – 124.84 Mb Chr 7: 132.46 – 132.49 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

BRISC complex subunit Abro1 is a protein that in humans is encoded by the FAM175B gene.

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.