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Jpx (gene)

From Wikipedia, the free encyclopedia
JPX
Identifiers
AliasesJPX, DCBALD06, ENOX, LINC00183, NCRNA00183, Jpx, JPX transcript, XIST activator (non-protein coding), JPX transcript, XIST activator
External IDsOMIM: 300832; GeneCards: JPX; OMA:JPX - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)Chr X: 73.94 – 74.07 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

In molecular biology, JPX transcript, XIST activator (non-protein coding), also known as Jpx, is a long non-coding RNA. In humans, it is located on the X chromosome. It was identified during sequence analysis of the X inactivation centre, surrounding the Xist gene.[3] Jpx upregulates expression of Xist.[4]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000225470Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Chureau C, Prissette M, Bourdet A, Barbe V, Cattolico L, Jones L, et al. (2002). "Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine". Genome Res. 12 (6): 894–908. doi:10.1101/gr.152902. PMC 1383731. PMID 12045143.
  4. ^ Tian D, Sun S, Lee JT (2010). "The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation". Cell. 143 (3): 390–403. doi:10.1016/j.cell.2010.09.049. PMC 2994261. PMID 21029862.

Further reading

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