JAKMIP2

JAKMIP2
Identifiers
Aliases	JAKMIP2, JAMIP2, NECC1, janus kinase and microtubule interacting protein 2
External IDs	OMIM: 611197; MGI: 1923467; HomoloGene: 8866; GeneCards: JAKMIP2; OMA:JAKMIP2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	147,782,775 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	43,820,838 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; sural nerve; ; middle temporal gyrus; ; ganglionic eminence; ; corpus callosum; ; dorsal motor nucleus of vagus nerve; ; entorhinal cortex; ; prefrontal cortex; ; postcentral gyrus; ; Brodmann area 46;
	Top expressed in
	habenula; ; piriform cortex; ; lobe of cerebellum; ; mammillary body; ; anterior amygdaloid area; ; ventromedial nucleus; ; subiculum; ; cerebellar vermis; ; lateral hypothalamus; ; primary motor cortex;
	More reference expression data
	n/a
Orthologs
	9832
	76217
	ENSG00000176049
	ENSMUSG00000024502
	Q96AA8
	D3YXK0
	NM_014790; NM_001270934; NM_001270941; NM_001282282
	NM_001163637
	NP_001257863; NP_001257870; NP_001269211; NP_055605
	NP_001157109
	Wikidata
View/Edit Human	View/Edit Mouse

Janus kinase and microtubule interacting protein 2 is a protein that in humans is encoded by the JAKMIP2 gene. ^[5]

Function

The protein encoded by this gene is reported to be a component of the Golgi matrix. It may act as a golgin protein by negatively regulating transit of secretory cargo and by acting as a structural scaffold of the Golgi. Alternative splicing results in multiple transcript variants.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000176049 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024502 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Janus kinase and microtubule interacting protein 2". Retrieved 2017-05-31.

Cruz-Garcia D, Vazquez-Martinez R, Peinado JR, Anouar Y, Tonon MC, Vaudry H, Castaño JP, Malagon MM (2007). "Identification and characterization of two novel (neuro)endocrine long coiled-coil proteins". FEBS Lett. 581 (17): 3149–56. doi:10.1016/j.febslet.2007.06.002. PMID 17572408. S2CID 29349416.
Koskinen LL, Einarsdottir E, Korponay-Szabo IR, Kurppa K, Kaukinen K, Sistonen P, Pocsai Z, Széles G, Adány R, Mäki M, Kere J, Saavalainen P (2009). "Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations". Tissue Antigens. 74 (5): 408–16. doi:10.1111/j.1399-0039.2009.01359.x. PMID 19845895.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000176049 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024502 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Janus kinase and microtubule interacting protein 2". Retrieved 2017-05-31.

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Function

References

Further reading