Imidocarb

Imidocarb
Names
	Preferred IUPAC name N,N′-Bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea
	Other names Imizocarb; Imizol; Diamidine
Identifiers
CAS Number	27885-92-3 ;
3D model (JSmol)	Interactive image;
ChemSpider	20102;
ECHA InfoCard	100.044.268
PubChem CID	21389;
UNII	8USS3K0VDH;
CompTox Dashboard (EPA)	DTXSID0048345 ;
	InChI InChI=1S/C19H20N6O/c26-19(24-15-5-1-3-13(11-15)17-20-7-8-21-17)25-16-6-2-4-14(12-16)18-22-9-10-23-18/h1-6,11-12H,7-10H2,(H,20,21)(H,22,23)(H2,24,25,26) Key: SCEVFJUWLLRELN-UHFFFAOYSA-N; InChI=1/C19H20N6O/c26-19(24-15-5-1-3-13(11-15)17-20-7-8-21-17)25-16-6-2-4-14(12-16)18-22-9-10-23-18/h1-6,11-12H,7-10H2,(H,20,21)(H,22,23)(H2,24,25,26) Key: SCEVFJUWLLRELN-UHFFFAOYAD;
	SMILES O=C(Nc2cc(C/1=N/CCN\1)ccc2)Nc3cccc(c3)/C4=N/CCN4;
Properties
Chemical formula	C19H20N6O
Molar mass	348.410 g·mol−1
Pharmacology
ATCvet code	QP51EX01 (WHO)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia (babesiosis) and other parasites.^[1]^[2]^[3]

Mechanism of action

^ Hashemi-Fesharki, R (1977). "Studies on imidocarb dihydrochloride in experimental Babesia ovis infection in splenectomized lambs". The British Veterinary Journal. 133 (6): 609–14. doi:10.1016/S0007-1935(17)33941-6. PMID 608109.
^ Hashemi-Fesharki, R (1975). "Studies on imidocarb dihydrochloride in experimental Babesia bigemina infection in calves". The British Veterinary Journal. 131 (6): 666–72. doi:10.1016/S0007-1935(17)35138-2. PMID 1212605.
^ Kuttler, KL (1980). "Pharmacotherapeutics of drugs used in treatment of anaplasmosis and babesiosis". Journal of the American Veterinary Medical Association. 176 (10 Spec No): 1103–8. PMID 7216881.
^ "Imidocarb". DrugBank. Retrieved November 23, 2024.
^ Papich, Mark G. (2016). Saunders Handbook of Veterinary Drugs (4th ed.). Elsevier. pp. 391–392. doi:10.1016/B978-0-323-24485-5.00304-1. ISBN 978-0-323-24485-5.

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