Homofentanyl

Homofentanyl
Identifiers
	IUPAC name N-phenyl-N-[1-(3-phenylpropyl)piperidin-4-yl]propanamide;
CAS Number	59708-54-2 ; 117332-88-4 (HCl);
PubChem CID	618626;
UNII	GBD33DI2IP;
CompTox Dashboard (EPA)	DTXSID701034384 ;
Chemical and physical data
Formula	C23H30N2O
Molar mass	350.506 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC(=O)N(C1CCN(CC1)CCCC2=CC=CC=C2)C3=CC=CC=C3;
	InChI InChI=1S/C23H30N2O/c1-2-23(26)25(21-13-7-4-8-14-21)22-15-18-24(19-16-22)17-9-12-20-10-5-3-6-11-20/h3-8,10-11,13-14,22H,2,9,12,15-19H2,1H3; Key:CKBFKWWOUYBCRH-UHFFFAOYSA-N;

Homofentanyl (N-Phenylpropylnorfentanyl, Fentanyl propyl analogue) is an opioid derivative which has been sold as a designer drug. It is a homologue of fentanyl, with similar analgesic and sedative effects but lower potency,^[1]^[2] around 14× stronger than pethidine.^[3]

References

^ Cooper D, Jacob M, Allen A (April 1986). "Identification of fentanyl derivatives". Journal of Forensic Sciences. 31 (2): 511–28. doi:10.1520/JFS12283J. PMID 3711827.
^ "Fentanyl-Related Substances with no Currently Known Legitimate Uses" (PDF). International Narcotics Control Board (INCB). 15 September 2020.
^ Casy AF, Parfitt RY (1986). Opioid analgesics, chemistry and receptors. New York: Plenum Press. p. 289. ISBN 978-0-306-42130-3.

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[pmid3711827-1] Cooper D, Jacob M, Allen A (April 1986). "Identification of fentanyl derivatives". Journal of Forensic Sciences. 31 (2): 511–28. doi:10.1520/JFS12283J. PMID 3711827.

[2] "Fentanyl-Related Substances with no Currently Known Legitimate Uses" (PDF). International Narcotics Control Board (INCB). 15 September 2020.

[3] Casy AF, Parfitt RY (1986). Opioid analgesics, chemistry and receptors. New York: Plenum Press. p. 289. ISBN 978-0-306-42130-3.

[1]

[2]

[3]

See also

References