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Histone cluster 2 h3 family member d

From Wikipedia, the free encyclopedia
H3C13
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesH3C13, histone cluster 2 H3 family member d, H3 clustered histone 13, HIST2H3D, H3C15, H3C14
External IDsMGI: 2448320; HomoloGene: 134489; GeneCards: H3C13; OMA:H3C13 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001123375

NM_175653

RefSeq (protein)

NP_066403
NP_001116847

Location (UCSC)Chr 1: 149.81 – 149.81 MbChr 13: 23.93 – 23.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Histone cluster 2 H3 family member d is a protein that in humans is encoded by the HIST2H3D gene. [5]

Function

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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. [provided by RefSeq, Aug 2015].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000183598Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000069310Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Histone cluster 2 H3 family member d". Retrieved 2018-05-17.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.