Haplogroup Q-NWT01
| Haplogroup Q-NWT01 | |
|---|---|
| Possible time of origin | 20,000-25,000 years before present[1] |
| Possible place of origin | Asia or Beringia |
| Ancestor | Q-MEH2 |
| Descendants | Q-M120[2], Q-B143 |
| Defining mutations | F746/NWT01 |
Haplogroup Q-NWT01 is a subclade of Y-DNA Haplogroup Q-MEH2.[3] Haplogroup Q-NWT01 is defined by the presence of the F746/NWT01 Single Nucleotide Polymorphism (SNP).
Distribution
[edit]Q-NWT01 has descendants in the Northwest Territories of modern Canada. It was in these populations that it was discovered.[3]
The Americas
[edit]Q-NWT01 is present in pre-Columbian populations in the Canadian Northwest.[3] However, subsequent genetic studies have indicated that samples previously reported as Q-NWT01 within Eskimo-Aleut populations are more likely to belong to the Q-B143 subclade.[4] It also has been found in a specimen of the Saqqaq culture of prehistoric Greenland.[5][6]
| Population | Paper | N | Percentage | SNP Tested | |
|---|---|---|---|---|---|
| Gwich’in | Dulik 2012 | 0/33 | ~0.00% | NWT01 | |
| Tłįchǫ | Dulik 2012 | 1/37 | ~2.70% | NWT01 | |
| Inuvialuit | Dulik 2012 | 25/56 | ~44.62% | NWT01 | |
| Inupiat | Dulik 2012 | 3/5 | ~60.00% | NWT01 |
Asia
[edit]Because few samples from Asia have been tested for this lineage, its frequency there is uncertain. However, haplogroup Q-M120 is spread widely in Asia, from Azerbaijan and Kalmykia in the west to Japan in the east and from Mongolia in the north to Brunei in the south, and the entire Q-M120 clade has been determined to be a subclade of Q-NWT01.[5] In addition, Y-DNA that belongs to the Q-B143 subclade like the Saqqaq specimen from Greenland has been found in Koryaks.[6]
Ancient DNA
[edit]Upper Paleolithic individual from the Afontova Gora 2 site, dating to approximately 17,000 years ago and representing the Ancient North Eurasian ancestry,[7] is the earliest known member of haplogroup Q1a1-F746.[8]
A 2023 study published in Nature found that haplogroup Q1a1-F746/NWT01 was highly prevalent among individuals from the Murzihinskiy II and Yuzhny Oleny archaeological sites in western Russia, dating back to c. 6,500 and 8,200 years ago, respectively.[9] These individuals exhibited genetic similarity to Eastern Hunter-Gatherers, suggesting that this haplogroup was widespread among early hunter-gatherer populations in the region.[10]
Associated SNPs
[edit]Q-NWT01 is currently defined by only the NWT01 SNP. As part of the National Geographic Geno 2.0 test, this SNP is labeled F746. This is because it was independently discovered in a Q-M120 sample sequenced with next generation technology.[2] It can also be called PR4083 as it was labeled in a primate sample sequenced at Family Tree DNA's Genomic Research Center.[2]
Phylogenetic Tree
[edit]
Source: ISOGG 2018.[8]
See also
[edit]Y-DNA Q-M242 subclades
[edit]Y-DNA backbone tree
[edit]
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Footnotes
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References
[edit]- ^ Wei et al. 2018, Figure S1.
- ^ a b c Family Tree DNA; Krahn, Thomas. "FTDNA Y Map". Retrieved 17 February 2013.
- ^ a b c Dulik, M. C.; Owings, A. C.; Gaieski, J. B.; Vilar, M. G.; Andre, A.; Lennie, C.; MacKenzie, M. A.; Kritsch, I.; et al. (2012). "Y-chromosome analysis reveals genetic divergence and new founding native lineages in Athapaskan- and Eskimoan-speaking populations". Proceedings of the National Academy of Sciences. 109 (22): 8471–6. Bibcode:2012PNAS..109.8471D. doi:10.1073/pnas.1118760109. PMC 3365193. PMID 22586127.
- ^ Wei, Lan-Hai; Wang, Ling-Xiang; Wen, Shao-Qing; Yan, Shi; Canada, Rebekah; Gurianov, Vladimir; Huang, Yun-Zhi; Mallick, Swapan; Biondo, Alessandro; O’Leary, Amy; Wang, Chuan-Chao; Lu, Yan; Zhang, Chao; Jin, Li; Xu, Shuhua (2018). "Paternal origin of Paleo-Indians in Siberia: insights from Y-chromosome sequences". European Journal of Human Genetics. 26 (11): 1687–1696. doi:10.1038/s41431-018-0211-6. ISSN 1476-5438. PMC 6189043. PMID 29991739.
- ^ a b YFull Haplogroup YTree v6.03.05 at 20 July 2018. Accessed July 20, 2018.
- ^ a b Monika Karmin, Lauri Saag, Mário Vicente, et al. (2015), "A recent bottleneck of Y chromosome diversity coincides with a global change in culture." Genome Research 25:1–8. Published by Cold Spring Harbor Laboratory Press; ISSN 1088-9051/15; www.genome.org.
- ^ Gill, Haechan; Lee, Juhyeon; Jeong, Choongwon (2024-04-02). "Reconstructing the Genetic Relationship between Ancient and Present-Day Siberian Populations". Genome Biology and Evolution. 16 (4): evae063. doi:10.1093/gbe/evae063. ISSN 1759-6653. PMC 10999361. PMID 38526010.
- ^ a b "ISOGG 2018 Y-DNA Haplogroup Q". isogg.org. Retrieved 2024-11-13.
- ^ Posth et al. 2023, Supplementary Data 1.A.
- ^ Posth, Cosimo; Yu, He; Ghalichi, Ayshin; Rougier, Hélène; Crevecoeur, Isabelle; Huang, Yilei; Ringbauer, Harald; Rohrlach, Adam B.; Nägele, Kathrin; Villalba-Mouco, Vanessa; Radzeviciute, Rita; Ferraz, Tiago; Stoessel, Alexander; Tukhbatova, Rezeda; Drucker, Dorothée G. (March 2023). "Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers". Nature. 615 (7950): 117–126. Bibcode:2023Natur.615..117P. doi:10.1038/s41586-023-05726-0. ISSN 1476-4687. PMC 9977688. PMID 36859578.