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Glutathione—homocystine transhydrogenase

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glutathione—homocystine transhydrogenase
Identifiers
EC no.1.8.4.1
CAS no.9029-40-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
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In enzymology, a glutathione—homocystine transhydrogenase (EC 1.8.4.1) is an enzyme that catalyzes the chemical reaction

2 glutathione + homocystine glutathione disulfide + 2 homocysteine

Thus, the two substrates of this enzyme are glutathione and homocystine, whereas its two products are glutathione disulfide and homocysteine.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is glutathione:homocystine oxidoreductase. This enzyme participates in methionine metabolism and glutathione metabolism.

References

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  • Racker, E. (December 1955). "Glutathione-homocystine transhydrogenase". Journal of Biological Chemistry. 217 (2): 867–874. doi:10.1016/s0021-9258(18)65951-4. ISSN 0021-9258. PMID 13271447.