Gandy–Gamna nodules

Gandy–Gamna nodules or Gandy-Gamna bodies, sometimes known as Gamna-Gandy bodies or Gamna-Gandy nodules, are small yellow-brown, brown, or rust-colored foci found in the spleen in patients with splenomegaly due to portal hypertension,^[1] as well as sickle cell disease. They consist of fibrous tissue with haemosiderin and calcium deposits, and probably form due to scarring at sites of small perivascular haemorrhages.^[2] They are visible on MRI scanning due to the presence of haemosiderin.^[3]

They can also be seen in atrial myxomas.

They are named after Charles Gandy and Carlos Gamna.

References

^ Kuntz, Erwin; Kuntz, Hans-Dieter (11 March 2009). Hepatology: Textbook and Atlas. Springer Science & Business Media. p. 253. ISBN 9783540768395. Prolonged portal hypertention sometimes leads to the formation of Gamna-Gandy nodules.
^ Gandy-Gamna bodies at Mondofacto online medical dictionary
^ Sagoh T, Itoh K, Togashi K, Shibata T, Nishimura K, Minami S, Asato R, Noma S, Fujisawa I, Yamashita K (1989). "Gamna-Gandy bodies of the spleen: evaluation with MR imaging". Radiology. 172 (3): 685–7. doi:10.1148/radiology.172.3.2672093. PMID 2672093.{{cite journal}}: CS1 maint: multiple names: authors list (link)

External links

Gandy-Gamna bodies at Who Named It?

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[KuntzKuntz2009-1] Kuntz, Erwin; Kuntz, Hans-Dieter (11 March 2009). Hepatology: Textbook and Atlas. Springer Science & Business Media. p. 253. ISBN 9783540768395. Prolonged portal hypertention sometimes leads to the formation of Gamna-Gandy nodules.

[2] Gandy-Gamna bodies at Mondofacto online medical dictionary

[3] Sagoh T, Itoh K, Togashi K, Shibata T, Nishimura K, Minami S, Asato R, Noma S, Fujisawa I, Yamashita K (1989). "Gamna-Gandy bodies of the spleen: evaluation with MR imaging". Radiology. 172 (3): 685–7. doi:10.1148/radiology.172.3.2672093. PMID 2672093.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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