Hydroxylysine kinase
(Redirected from GTP:5-hydroxy-L-lysine O-phosphotransferase)
| hydroxylysine kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.1.81 | ||||||||
| CAS no. | 9073-58-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a hydroxylysine kinase (EC 2.7.1.81) is an enzyme that catalyzes the chemical reaction
- GTP + 5-hydroxy-L-lysine GDP + 5-phosphonooxy-L-lysine
Thus, the two substrates of this enzyme are GTP and 5-hydroxy-L-lysine, whereas its two products are GDP and 5-phosphonooxy-L-lysine.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is GTP:5-hydroxy-L-lysine O-phosphotransferase. Other names in common use include hydroxylysine kinase (phosphorylating), and guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase. This enzyme participates in lysine degradation.
References
[edit]- Hiles RA, Henderson LM (1972). "The partial purification and properties of hydroxylysine kinase from rat liver". J. Biol. Chem. 247 (3): 646–51. PMID 4621658.
