Jump to content

GATAD2B

From Wikipedia, the free encyclopedia

GATAD2B
Identifiers
AliasesGATAD2B, MRD18, P66beta, p68, GATA zinc finger domain containing 2B, GANDS
External IDsOMIM: 614998; MGI: 2443225; HomoloGene: 32484; GeneCards: GATAD2B; OMA:GATAD2B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020699

NM_139304
NM_001379655
NM_001379656
NM_001379657

RefSeq (protein)

NP_065750

NP_647465
NP_001366584
NP_001366585
NP_001366586

Location (UCSC)Chr 1: 153.79 – 153.92 MbChr 3: 90.2 – 90.27 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transcriptional repressor p66-beta is a protein that in humans is encoded by the GATAD2B gene.[5][6][7]


Interactions

[edit]

GATAD2B has been shown to interact with Methyl-CpG-binding domain protein 2,[6][8] MBD3,[6][8] RBBP7[6] and RBBP4.[6]

References

[edit]
  1. ^ a b c ENSG00000261992 GRCh38: Ensembl release 89: ENSG00000143614, ENSG00000261992Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042390Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O (Jan 2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi:10.1093/dnares/6.5.329. PMID 10574461. S2CID 263221761.
  6. ^ a b c d e Feng Q, Cao R, Xia L, Erdjument-Bromage H, Tempst P, Zhang Y (Dec 2001). "Identification and functional characterization of the p66/p68 components of the MeCP1 complex". Mol Cell Biol. 22 (2): 536–46. doi:10.1128/MCB.22.2.536-546.2002. PMC 139742. PMID 11756549.
  7. ^ "Entrez Gene: GATAD2B GATA zinc finger domain containing 2B".
  8. ^ a b Brackertz M, Boeke Joern, Zhang Ru, Renkawitz Rainer (Oct 2002). "Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3". J. Biol. Chem. 277 (43). United States: 40958–66. doi:10.1074/jbc.M207467200. ISSN 0021-9258. PMID 12183469.

Further reading

[edit]