FOXJ2

FOXJ2
Identifiers
Aliases	FOXJ2, FHX, forkhead box J2
External IDs	MGI: 1926805; HomoloGene: 10187; GeneCards: FOXJ2; OMA:FOXJ2 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	8,055,517 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	122,822,325 bp
RNA expression pattern
	Top expressed in
	nipple; ; saphenous vein; ; cardia; ; vena cava; ; body of tongue; ; thoracic diaphragm; ; superior surface of tongue; ; Skeletal muscle tissue of rectus abdominis; ; pylorus; ; pericardium;
	Top expressed in
	ankle; ; inner renal medulla; ; thin ascending limb of loop of Henle; ; triceps brachii muscle; ; extraocular muscle; ; vastus lateralis muscle; ; granulocyte; ; temporal muscle; ; ciliary body; ; ascending aorta;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific DNA binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding; identical protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; fibrillar center;
Biological process	positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; anatomical structure morphogenesis; cell differentiation; negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell differentiation; positive regulation of vascular associated smooth muscle cell proliferation;
	Sources:Amigo / QuickGO
Orthologs
	55810
	60611
	ENSG00000065970
	ENSMUSG00000003154
	Q9P0K8
	Q9ES18
	NM_018416
	NM_021899
	NP_060886
	NP_068699
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box protein J2 is a protein that in humans is encoded by the FOXJ2 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000065970 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003154 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Perez-Sanchez C, Gomez-Ferreria MA, de La Fuente CA, Granadino B, Velasco G, Esteban-Gamboa A, Rey-Campos J (Jun 2000). "FHX, a novel fork head factor with a dual DNA binding specificity". J Biol Chem. 275 (17): 12909–16. doi:10.1074/jbc.275.17.12909. hdl:10261/168715. PMID 10777590.
^ Perez-Sanchez C, Arias-de-la-Fuente C, Gomez-Ferreria MA, Granadino B, Rey-Campos J (Sep 2000). "FHX.L and FHX.S, two isoforms of the human fork-head factor FHX (FOXJ2) with differential activity". J Mol Biol. 301 (4): 795–806. doi:10.1006/jmbi.2000.3999. PMID 10966786.
^ "Entrez Gene: FOXJ2 forkhead box J2".

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gómez-Ferrería MA, Rey-Campos J (2003). "Functional domains of FOXJ2". J. Mol. Biol. 329 (4): 631–44. doi:10.1016/S0022-2836(03)00524-2. PMID 12787665.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000065970 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000003154 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10777590-5] Perez-Sanchez C, Gomez-Ferreria MA, de La Fuente CA, Granadino B, Velasco G, Esteban-Gamboa A, Rey-Campos J (Jun 2000). "FHX, a novel fork head factor with a dual DNA binding specificity". J Biol Chem. 275 (17): 12909–16. doi:10.1074/jbc.275.17.12909. hdl:10261/168715. PMID 10777590.

[pmid10966786-6] Perez-Sanchez C, Arias-de-la-Fuente C, Gomez-Ferreria MA, Granadino B, Rey-Campos J (Sep 2000). "FHX.L and FHX.S, two isoforms of the human fork-head factor FHX (FOXJ2) with differential activity". J Mol Biol. 301 (4): 795–806. doi:10.1006/jmbi.2000.3999. PMID 10966786.

[entrez-7] "Entrez Gene: FOXJ2 forkhead box J2".

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References

Further reading