Endonuclease/exonuclease/phosphatase family domain containing 1

EEPD1
Identifiers
Aliases	EEPD1, HSPC107, endonuclease/exonuclease/phosphatase family domain containing 1
External IDs	OMIM: 617192; MGI: 1914734; HomoloGene: 12144; GeneCards: EEPD1; OMA:EEPD1 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) Band 7p14.2 Start 36,153,254 bp End 36,301,538 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 A4 Start 25,392,843 bp End 25,515,406 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone muscle of thigh gastrocnemius muscle gallbladder ganglionic eminence C1 segment body of stomach subcutaneous adipose tissue right lobe of liver pancreatic ductal cell Top expressed in muscle of thigh lumbar spinal ganglion extensor digitorum longus muscle plantaris muscle gastrocnemius muscle masseter muscle triceps brachii muscle quadriceps femoris muscle medial head of gastrocnemius muscle digastric muscle More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 80820 67484 Ensembl ENSG00000122547 ENSMUSG00000036611 UniProt Q7L9B9 Q3TGW2 RefSeq (mRNA) NM_030636 NM_026189 RefSeq (protein) NP_085139 NP_080465 Location (UCSC) Chr 7: 36.15 – 36.3 Mb Chr 9: 25.39 – 25.52 Mb PubMed search
Wikidata
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Endonuclease/exonuclease/phosphatase family domain containing 1 is a protein that in humans is encoded by the EEPD1 gene.

Further reading

• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
• Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, Kong K, Wu X, Kim HS, Beissbarth T, Gaedcke J, Burma S, Nickoloff JA, Hromas RA (December 2015). "EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair". PLOS Genet. 11 (12): e1005675. doi:10.1371/journal.pgen.1005675. PMC 4684289. PMID 26684013.
• Kim HS, Nickoloff JA, Wu Y, Williamson EA, Sidhu GS, Reinert BL, Jaiswal AS, Srinivasan G, Patel B, Kong K, Burma S, Lee SH, Hromas RA (February 2017). "Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks". J. Biol. Chem. 292 (7): 2795–2804. doi:10.1074/jbc.M116.758235. PMC 5314175. PMID 28049724.