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Elizabeth Anne Bukusi

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Elizabeth Anne Bukusi FAAS is a research professor working within the field of obstetrics and gynaecology, and global health.[1][2] Bukusi's main areas of research focus around sexually transmitted infections, women's health, reproductive health, and HIV care, prevention and treatment.[1][3] Bukusi is the Chief Research Officer at the Kenya Medical Research Institute (KEMRI) and led a "landmark" study on the use of PrEP in Kenya.[4][5]

Education

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Bukusi gained her general medical degree, followed by her Masters in obstetrics and gynaecology from the University of Nairobi.[1] She then went on to earn a certificate in international health, Masters in public health (MPH) and a PhD from the University of Washington's Department of Epidemiology.[1] Subsequent qualifications include a post-graduate diploma in Research ethics from the University of Cape Town, then a Masters in Bioethics from the Sind Institute of Urology and Transplantation.[1]

Research

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Bukusi's Masters in Public Health, completed in 2000, studied the male factor in bacterial vaginosis in Kenya, and her PhD then continued this path of research with her thesis titled: 'Bacterial Vaginosis: A Randomized Trial to Reduce Recurrence'. In 2006 Bukusi was awarded her PhD, and published a paper in the journal Sexually Transmitted Diseases, 'Bacterial vaginosis: risk factors among Kenyan women and their male partners'.[6]

In 2010 Bukusi published 'Genital hygiene practices of fishermen targeted for a topical microbicide intervention against sexually transmitted infections in Kisumu, Kenya', within the International Journal of STD and AIDS.[7]

Bukusi's academic roles include chief research officer at KEMRI;[3] chair of the Bioethics Society of Kenya;[8] research professor at the University of Washington;[1] honorary lecturer at Aga Khan University;[9] and volunteer clinical faculty professor at the University of California San Francisco.[1] Other outstanding studies she has participated in include; Association between Mycoplasma genitalium and acute endometritis.[10] Bacterial vaginosis associated with increased risk of Female-to-Male HIV-1 transmission: A prospective cohort analysis among African couples.[11] HIV/AIDS stigma and refusal of HIV testing among pregnant women in rural Kenya: Results from the MAMAS study. This study found that anticipations of HIV/AIDS stigma can be barriers to acceptance of HIV testing by pregnant women.[12] HIV pre-exposure prophylaxis for adolescent girls and young women in Africa: from efficacy trials to delivery. This article concluded that PrEP is feasible to implement in integrated reproductive health service delivery models to reach African AGYW.[13] Retention in care and patient-reported reasons for undocumented transfer or stopping care among HIV-infected patients on Antiretroviral therapy in Eastern Africa: application of a sampling-based approach.[14] Efficacy of isoniazid prophylactic therapy in prevention of tuberculosis in children: a meta–analysis.[15] Efficacy of single-dose human Papillomavirus vaccination among young African women.[16] Texting improves testing: a randomized trial of two-way SMS to increase postpartum prevention of mother-to-child transmission retention and infant HIV testing. This study established that text messaging significantly improved maternal postpartum visit attendance, but overall return rates for these visits remained low.[17] Efficacy of pre-exposure prophylaxis for HIV-1 prevention among high risk heterosexuals: subgroup analyses from the Partners PrEP Study. The study concluded that among higher-risk subgroups in the Partners PrEP Study, including groups solely of higher-risk women, both TDF alone and combined FTC/TDF PrEP had consistently high efficacy for HIV-1 protection.[18] Family model of HIV care and treatment: a retrospective study in Kenya.[19] Rethinking HIV prevention to prepare for oral PrEP implementation for young African women.[20] Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.[21] HIV incidence among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: a randomised, multicentre, open-label trial. This study did not find a substantial difference in HIV risk among the methods evaluated, and all methods were safe and highly effective.[22] Cervical cancer prevention and treatment research in Africa: a systematic review from a public health perspective.[23] and Integrated delivery of antiretroviral treatment and Pre-exposure Prophylaxis to HIV-1–Serodiscordant couples: A prospective implementation study in Kenya and Uganda.[24]

References

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  1. ^ a b c d e f g "Elizabeth Bukusi | University of Washington - Department of Global Health". globalhealth.washington.edu. Retrieved 2019-10-02.
  2. ^ "Professor Elizabeth Anne Bukusi — Ethox Centre". www.ethox.ox.ac.uk. Retrieved 2019-10-02.
  3. ^ a b "Elizabeth Bukusi, MBChB, MMed, MPH, PhD". Kenya Research and Training Center. Archived from the original on 2017-11-11. Retrieved 2019-10-02.
  4. ^ "The unsung hero: Why Elizabeth Bukusi deserves accolades". The Star. Retrieved 2019-10-02.
  5. ^ "Study proves 7,000 AIDS deaths can be prevented annually in Kenya". The Star. Retrieved 2019-10-02.
  6. ^ Bukusi, Elizabeth A.; Cohen, Craig R.; Meier, Amalia S.; Waiyaki, Peter G.; Nguti, Rosemary; Njeri, Jane N.; Holmes, King K. (June 2006). "Bacterial Vaginosis: Risk Factors Among Kenyan Women and Their Male Partners". Sexually Transmitted Diseases. 33 (6): 361–367. doi:10.1097/01.olq.0000200551.07573.df. ISSN 0148-5717. PMID 16547451. S2CID 74319392.
  7. ^ Kwena, Z A; Bukusi, E A; Gorbach, P; Sharma, A; Sang, N M; Holmes, K K (June 2010). "Genital hygiene practices of fishermen targeted for a topical microbicide intervention against sexually transmitted infections in Kisumu, Kenya". International Journal of STD & AIDS. 21 (6): 435–440. doi:10.1258/ijsa.2010.010103. ISSN 0956-4624. PMC 6456332. PMID 20606226.
  8. ^ "Kenyan researchers rise to meet the complex challenges of Bioethics". The Star. Retrieved 2019-10-02.
  9. ^ "Bukusi Elizabeth Anne | The AAS". aasciences.ac.ke. Retrieved 2019-10-02.[permanent dead link]
  10. ^ Cohen, Craig R; Manhart, Lisa E; Bukusi, Elizabeth A; Astete, Sabina; Brunham, Robert C; Holmes, King K; Sinei, Samuel K; Bwayo, Job J; Totten, Patricia A (2002-03-02). "Association between Mycoplasma genitalium and acute endometritis". The Lancet. 359 (9308): 765–766. doi:10.1016/S0140-6736(02)07848-0. ISSN 0140-6736. PMID 11888591. S2CID 36191700.
  11. ^ Cohen, Craig R.; Lingappa, Jairam R.; Baeten, Jared M.; Ngayo, Musa O.; Spiegel, Carol A.; Hong, Ting; Donnell, Deborah; Celum, Connie; Kapiga, Saidi; Delany, Sinead; Bukusi, Elizabeth A. (2012-06-26). "Bacterial Vaginosis Associated with Increased Risk of Female-to-Male HIV-1 Transmission: A Prospective Cohort Analysis among African Couples". PLOS Medicine. 9 (6): e1001251. doi:10.1371/journal.pmed.1001251. ISSN 1549-1676. PMC 3383741. PMID 22745608.
  12. ^ Turan, Janet M.; Bukusi, Elizabeth A.; Onono, Maricianah; Holzemer, William L.; Miller, Suellen; Cohen, Craig R. (2011-08-01). "HIV/AIDS Stigma and Refusal of HIV Testing Among Pregnant Women in Rural Kenya: Results from the MAMAS Study". AIDS and Behavior. 15 (6): 1111–1120. doi:10.1007/s10461-010-9798-5. ISSN 1573-3254. PMC 3127002. PMID 20827573.
  13. ^ Celum, Connie L; Delany-Moretlwe, Sinead; Baeten, Jared M; Straten, Ariane; Hosek, Sybil; Bukusi, Elizabeth A; McConnell, Margaret; Barnabas, Ruanne V; Bekker, Linda-Gail (2019). "HIV pre-exposure prophylaxis for adolescent girls and young women in Africa: from efficacy trials to delivery". Journal of the International AIDS Society. 22 (S4): e25298. doi:10.1002/jia2.25298. ISSN 1758-2652. PMC 6643076. PMID 31328444. S2CID 198133013.
  14. ^ Geng, Elvin H. (2015). "Retention in Care and Patient-Reported Reasons for Undocumented Transfer or Stopping Care Among HIV-Infected Patients on Antiretroviral Therapy in Eastern Africa: Application of a Sampling-Based Approach". Clinical Infectious Diseases. 62 (7): 935–944. doi:10.1093/cid/civ1004. PMC 4787603. PMID 26679625.
  15. ^ Ayieko, James; Abuogi, Lisa; Simchowitz, Brett; Bukusi, Elizabeth A.; Smith, Allan H.; Reingold, Arthur (2014-02-20). "Efficacy of isoniazid prophylactic therapy in prevention of tuberculosis in children: a meta–analysis". BMC Infectious Diseases. 14 (1): 91. doi:10.1186/1471-2334-14-91. ISSN 1471-2334. PMC 3936889. PMID 24555539.
  16. ^ Barnabas, Ruanne V.; Brown, Elizabeth R.; Onono, Maricianah A.; Bukusi, Elizabeth A.; Njoroge, Betty; Winer, Rachel L.; Galloway, Denise A.; Pinder, Leeya F.; Donnell, Deborah; Wakhungu, Imelda; Congo, Ouma; Biwott, Charlene; Kimanthi, Syovata; Oluoch, Lynda; Heller, Kate B. (2022-04-26). "Efficacy of Single-Dose Human Papillomavirus Vaccination among Young African Women". NEJM Evidence. 1 (5): EVIDoa2100056. doi:10.1056/EVIDoa2100056. ISSN 2766-5526. PMC 9172784. PMID 35693874.
  17. ^ Odeny, Thomas A.; Bukusi, Elizabeth A.; Cohen, Craig R.; Yuhas, Krista; Camlin, Carol S.; McClelland, R. Scott (2014-09-24). "Texting improves testing: a randomized trial of two-way SMS to increase postpartum prevention of mother-to-child transmission retention and infant HIV testing". AIDS. 28 (15): 2307–2312. doi:10.1097/QAD.0000000000000409. ISSN 0269-9370. PMC 4834137. PMID 25313586.
  18. ^ Murnane, Pamela M.; Celum, Connie; Mugo, Nelly; Campbell, James D.; Donnell, Deborah; Bukusi, Elizabeth; Mujugira, Andrew; Tappero, Jordan; Kahle, Erin M.; Thomas, Katherine K.; Baeten, Jared M. (2013-08-24). "Efficacy of preexposure prophylaxis for HIV-1 prevention among high-risk heterosexuals: subgroup analyses from a randomized trial". AIDS. 27 (13): 2155–2160. doi:10.1097/QAD.0b013e3283629037. ISSN 0269-9370. PMC 3882910. PMID 24384592.
  19. ^ Lewis Kulzer, Jayne; Penner, Jeremy A; Marima, Reson; Oyaro, Patrick; Oyanga, Arbogast O; Shade, Starley B; Blat, Cinthia C; Nyabiage, Lennah; Mwachari, Christina W; Muttai, Hellen C; Bukusi, Elizabeth A; Cohen, Craig R (2012). "Family model of HIV care and treatment: a retrospective study in Kenya". Journal of the International AIDS Society. 15 (1): 8. doi:10.1186/1758-2652-15-8. ISSN 1758-2652. PMC 3298805. PMID 22353553.
  20. ^ Celum, Connie L; Delany-Moretlwe, Sinead; McConnell, Margaret; van Rooyen, Heidi; Bekker, Linda-Gail; Kurth, Ann; Bukusi, Elizabeth; Desmond, Chris; Morton, Jennifer; Baeten, Jared M (2015). "Rethinking HIV prevention to prepare for oral PrEP implementation for young African women". Journal of the International AIDS Society. 18 (4 Suppl 3): 20227. doi:10.7448/IAS.18.4.20227. PMC 4509892. PMID 26198350.
  21. ^ Baeten, Jared M.; Donnell, Deborah; Ndase, Patrick; Mugo, Nelly R.; Campbell, James D.; Wangisi, Jonathan; Tappero, Jordan W.; Bukusi, Elizabeth A.; Cohen, Craig R.; Katabira, Elly; Ronald, Allan; Tumwesigye, Elioda; Were, Edwin; Fife, Kenneth H.; Kiarie, James (2012-08-02). "Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women". New England Journal of Medicine. 367 (5): 399–410. doi:10.1056/NEJMoa1108524. ISSN 0028-4793. PMC 3770474. PMID 22784037.
  22. ^ Ahmed, Khatija; Baeten, Jared M; Beksinska, Mags; Bekker, Linda-Gail; Bukusi, Elizabeth A; Donnell, Deborah; Gichangi, Peter B; Heller, Kate B; Hofmeyr, G Justus; Justman, Jessica; Kasaro, Margaret Phiri; Kiarie, James; Louw, Cheryl; Mastro, Timothy D; Morrison, Charles S (2019-07-27). "HIV incidence among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: a randomised, multicentre, open-label trial". The Lancet. 394 (10195): 303–313. doi:10.1016/S0140-6736(19)31288-7. ISSN 0140-6736. PMC 6675739. PMID 31204114. S2CID 186245753.
  23. ^ Finocchario-Kessler, Sarah; Wexler, Catherine; Maloba, May; Mabachi, Natabhona; Ndikum-Moffor, Florence; Bukusi, Elizabeth (2016-06-04). "Cervical cancer prevention and treatment research in Africa: a systematic review from a public health perspective". BMC Women's Health. 16 (1): 29. doi:10.1186/s12905-016-0306-6. ISSN 1472-6874. PMC 4893293. PMID 27259656.
  24. ^ Baeten, Jared M.; Heffron, Renee; Kidoguchi, Lara; Mugo, Nelly R.; Katabira, Elly; Bukusi, Elizabeth A.; Asiimwe, Stephen; Haberer, Jessica E.; Morton, Jennifer; Ngure, Kenneth; Bulya, Nulu; Odoyo, Josephine; Tindimwebwa, Edna; Hendrix, Craig; Marzinke, Mark A. (2016-08-23). "Integrated Delivery of Antiretroviral Treatment and Pre-exposure Prophylaxis to HIV-1–Serodiscordant Couples: A Prospective Implementation Study in Kenya and Uganda". PLOS Medicine. 13 (8): e1002099. doi:10.1371/journal.pmed.1002099. ISSN 1549-1676. PMC 4995047. PMID 27552090.
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