EXPH5

EXPH5
Identifiers
Aliases	EXPH5, SLAC2-B, SLAC2B, exophilin 5, EBS4
External IDs	OMIM: 612878; MGI: 2443248; HomoloGene: 9007; GeneCards: EXPH5; OMA:EXPH5 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	108,593,768 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	53,288,814 bp
RNA expression pattern
	Top expressed in
	skin of hip; ; mucosa of paranasal sinus; ; amniotic fluid; ; oral cavity; ; skin of thigh; ; bronchial epithelial cell; ; skin of arm; ; nipple; ; nasal epithelium; ; gums;
	Top expressed in
	cerebellar cortex; ; jejunum; ; zone of skin; ; liver; ; ileum; ; esophagus; ; lip; ; stomach; ; spermatocyte; ; lung;
	More reference expression data
	More reference expression data
Orthologs
	23086
	320051
	ENSG00000110723
	ENSMUSG00000034584
	Q8NEV8
	Q0VAV2
	NM_001144763; NM_001144764; NM_001144765; NM_001308019; NM_015065
	NM_176846
	NP_001138235; NP_001138236; NP_001138237; NP_001294948; NP_055880
	NP_789816
	Wikidata
View/Edit Human	View/Edit Mouse

Exophilin 5, also known as EXPH5, is a human gene.^[5]

Interactions

EXPH5 has been shown to interact with RAB27A.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000110723 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034584 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: EXPH5 exophilin 5".
^ Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (Mar 2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". J. Biol. Chem. 277 (11): 9212–8. doi:10.1074/jbc.M112414200. PMID 11773082.

Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Fukuda M (2003). "Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells". J. Biol. Chem. 278 (17): 15390–6. doi:10.1074/jbc.M213090200. PMID 12590134.
Fukuda M (2002). "Synaptotagmin-like protein (Slp) homology domain 1 of Slac2-a/melanophilin is a critical determinant of GTP-dependent specific binding to Rab27A". J. Biol. Chem. 277 (42): 40118–24. doi:10.1074/jbc.M205765200. PMID 12189142.
Nagashima K, Torii S, Yi Z, Igarashi M, Okamoto K, Takeuchi T, Izumi T (2002). "Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions". FEBS Lett. 517 (1–3): 233–8. Bibcode:2002FEBSL.517..233N. doi:10.1016/S0014-5793(02)02634-0. PMID 12062444. S2CID 14844547.
Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". J. Biol. Chem. 277 (11): 9212–8. doi:10.1074/jbc.M112414200. PMID 11773082.
Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000110723 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034584 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: EXPH5 exophilin 5".

[pmid11773082-6] Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (Mar 2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". J. Biol. Chem. 277 (11): 9212–8. doi:10.1074/jbc.M112414200. PMID 11773082.

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Interactions

References

Further reading