EFCAB6

EFCAB6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WLZ, 5D67
Identifiers
Aliases	EFCAB6, DJBP, HSCBCIP1, dJ185D5.1, EF-hand calcium binding domain 6
External IDs	MGI: 1924877; HomoloGene: 11259; GeneCards: EFCAB6; OMA:EFCAB6 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	43,812,337 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	83,949,580 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; sperm; ; buccal mucosa cell; ; right uterine tube; ; bronchial epithelial cell; ; oocyte; ; testicle; ; olfactory zone of nasal mucosa; ; gonad;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; zygote; ; primary oocyte; ; secondary oocyte; ; muscle of thigh; ; temporal muscle; ; cornea; ; skeletal muscle tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; calcium ion binding;
Cellular component	nucleus; nucleoplasm;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	64800
	77627
	ENSG00000186976
	ENSMUSG00000022441
	Q5THR3
	Q6P1E8
	NM_022785; NM_198856
	NM_001161628; NM_001161629; NM_029946
	NP_073622; NP_942153
	NP_001155100; NP_001155101; NP_084222
	Wikidata
View/Edit Human	View/Edit Mouse

EF-hand calcium-binding domain-containing protein 6 is a protein that in humans is encoded by the EFCAB6 gene.^[5]^[6]^[7]

Interactions

EFCAB6 has been shown to interact with PARK7^[6] and Androgen receptor.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186976 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022441 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hirosawa M, Nagase T, Murahashi Y, Kikuno R, Ohara O (Mar 2001). "Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping". DNA Res. 8 (1): 1–9. doi:10.1093/dnares/8.1.1. PMID 11258795.
^ ^a ^b ^c Niki T, Takahashi-Niki K, Taira T, Iguchi-Ariga SM, Ariga H (Mar 2003). "DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex". Mol Cancer Res. 1 (4): 247–61. PMID 12612053.
^ "Entrez Gene: FLJ23588 CAP-binding protein complex interacting protein 1".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi:10.1038/990031. PMID 10591208.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954. PMID 12529303.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article on a gene on human chromosome 22 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000186976 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022441 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11258795-5] Hirosawa M, Nagase T, Murahashi Y, Kikuno R, Ohara O (Mar 2001). "Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping". DNA Res. 8 (1): 1–9. doi:10.1093/dnares/8.1.1. PMID 11258795.

[pmid12612053-6] Niki T, Takahashi-Niki K, Taira T, Iguchi-Ariga SM, Ariga H (Mar 2003). "DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex". Mol Cancer Res. 1 (4): 247–61. PMID 12612053.

[entrez-7] "Entrez Gene: FLJ23588 CAP-binding protein complex interacting protein 1".

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Interactions

References

Further reading