Draft:Silvia Rouskin
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Prof. Silvi Rouskin | |
|---|---|
| Born | |
| Other names | Silvia Rouskin |
| Citizenship | USA, Bulgaria |
| Awards | Vilcek Prize 2021, Pew Scholar 2024 |
| Academic background | |
| Alma mater | |
| Thesis | Investigating RNA structure and function, transcriptome-wide (2014) |
| Doctoral advisor | Jonathan Weissman |
| Academic work | |
| Discipline | |
| Main interests | |
| Notable works | DMSMaP-seq, DREEM |
Silvi Rouskin is a molecular biologist and Assistant Professor of Microbiology at Harvard Medical School..[1] Her research focuses on RNA, RNA alternative 2 and 3-dimensional structures, and alternative splicing of RNA.[2] Rouskin is well known for developing the DMS-MaPseq and DREEM methods, and for modeling the secondary structure of SARS-CoV-2 [3] [4] [5]
Early life and education
[edit]Rouskin was born in People's Republic of Bulgaria. Her parents were rock musicians, who made most of their career in Norway. Rouskin was raised by her grandparents until age six. As the Bulgarian communist regime collapsed in 1991, she moved to the state of Idaho in 1998 for her high-school junior year, as part of a student exchange program with the USA. [6]
At 16 years old, Rouskin passed the General Educational Development and enrolled in the Florida Institute of Technology as a freshman, where she obtained a BS in Physics.
After being a technical assistant at Joe DeRisi's lab, Rouskin completed her Ph.D. in Biochemistry and Molecular Biology in 2014 at UCSF School of Medicine.[7]
Career
[edit]In 2015, Rouskin became a Whitehead Fellow at the Whitehead Institute, a non-profit institute located in Massachusetts Institute of Technology.[8]
She is an Assistant Professor at Harvard Medical School since 2021.[9]
Selected awards
[edit]Selected publications
[edit]- Rouskin, S., Zubradt, M., Washietl, S., Kellis, M. and Weissman, J.S., 2014. Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo. Nature, 505(7485), pp.701-705.
- Zubradt, M., Gupta, P., Persad, S., Lambowitz, A.M., Weissman, J.S. and Rouskin, S., 2017. DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo. Nature methods, 14(1), pp.75-82.
- Tomezsko, P.J., Corbin, V.D., Gupta, P., Swaminathan, H., Glasgow, M., Persad, S., Edwards, M.D., Mcintosh, L., Papenfuss, A.T., Emery, A. and Swanstrom, R., 2020. Determination of RNA structural diversity and its role in HIV-1 RNA splicing. Nature, 582(7812), pp.438-442.
- Lan, T. C., Allan, M. F., Malsick, L. E., Woo, J. Z., Zhu, C., Zhang, F., ... & Rouskin, S. (2022). Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cells. Nature communications, 13(1), 1-14.
- Moran JC, Brivanlou A, Brischigliaro M, Fontanesi F*, Rouskin S*, Barrientos A*. The human mitochondrial mRNA structurome reveals mechanisms of gene expression. Science. 2024 Jul 19;385(6706)
See also
[edit]References
[edit]- ^ "Faculty". micro.hms.harvard.edu.
- ^ "ROUSKIN LAB". ROUSKIN LAB.
- ^ https://www.nature.com/articles/s41467-022-28603-2
- ^ Zubradt, Meghan; Gupta, Paromita; Persad, Sitara; Lambowitz, Alan M.; Weissman, Jonathan S.; Rouskin, Silvi (January 30, 2017). "DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo". Nature Methods. 14 (1): 75–82. doi:10.1038/nmeth.4057. PMC 5508988. PMID 27819661.
- ^ Tomezsko, P. J.; Corbin, V.; Gupta, P.; Swaminathan, H.; Glasgow, M.; Persad, S.; Edwards, M. D.; McIntosh, L.; Papenfuss, A. T.; Emery, A.; Swanstrom, R.; Zang, T.; Lan, T. C.; Bieniasz, P.; Kuritzkes, D. R.; Tsibris, A.; Rouskin, S. (2020). "Determination of RNA structural diversity and its role in HIV-1 RNA splicing - PMC". Nature. 582 (7812): 438–442. Bibcode:2020Natur.582..438T. doi:10.1038/s41586-020-2253-5. PMC 7310298. PMID 32555469.
- ^ "Silvi Rouskin: Exploring Life's Non-Linear Paths". Whitehead Institute of MIT.
- ^ a b "Silvi Rouskin". Vilcek Foundation.
- ^ "Whitehead in NYC with Fellows Olivia Corradin and Silvi Rouskin". whitehead542.rssing.com.
- ^ "Two Whitehead Fellows named to MIT and Harvard faculties". Whitehead Institute of MIT.
- ^ https://hria.org/wp-content/uploads/2016/02/Alumni_Directory_1992-2021.pdf
- ^ "Two students win Weintraub Awards". cmp.ucsf.edu.
- ^ http://www.bwfund.org/wp-content/uploads/2020/11/BWF-2018-Annual-Report_v15.pdf
- ^ https://www.pewtrusts.org/en/projects/pew-biomedical-scholars/directory-of-pew-scholars/2024/silvi-rouskin
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