DYNC1LI2

DYNC1LI2
Identifiers
Aliases	DYNC1LI2, DNCLI2, LIC2, dynein cytoplasmic 1 light intermediate chain 2
External IDs	OMIM: 611406; MGI: 107738; HomoloGene: 4474; GeneCards: DYNC1LI2; OMA:DYNC1LI2 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) Band 16q22.1 Start 66,720,893 bp End 66,751,609 bp
Gene location (Mouse) Chr. Chromosome 8 (mouse) Band 8 D3|8 53.04 cM Start 105,144,312 bp End 105,169,679 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell inferior ganglion of vagus nerve pars reticulata subthalamic nucleus external globus pallidus internal globus pallidus pars compacta Brodmann area 23 superior vestibular nucleus Pons Top expressed in central gray substance of midbrain hand neural layer of retina globus pallidus superior frontal gyrus cerebellar cortex deep cerebellar nuclei inferior colliculi medial geniculate nucleus pontine nuclei More reference expression data BioGPS More reference expression data
Gene ontology Molecular function microtubule motor activity nucleotide binding cytoskeletal motor activity ATP binding dynein heavy chain binding Cellular component cytoplasm cytosol membrane dynein complex microtubule cytoskeleton cytoplasmic dynein complex kinetochore lysosome late endosome centrosome Biological process antigen processing and presentation of exogenous peptide antigen via MHC class II centrosome localization endoplasmic reticulum to Golgi vesicle-mediated transport microtubule cytoskeleton organization microtubule-based movement sister chromatid cohesion transport protein homooligomerization cellular response to nerve growth factor stimulus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1783 234663 Ensembl ENSG00000135720 ENSMUSG00000035770 UniProt O43237 Q6PDL0 RefSeq (mRNA) NM_001286157 NM_006141 NM_001323955 NM_001013380 RefSeq (protein) NP_001273086 NP_001310884 NP_006132 NP_006132.1 NP_001013398 Location (UCSC) Chr 16: 66.72 – 66.75 Mb Chr 8: 105.14 – 105.17 Mb PubMed search
Wikidata
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Cytoplasmic dynein 1 light intermediate chain 2 is a protein that in humans is encoded by the DYNC1LI2 gene.

Further reading

• Hughes SM, Vaughan KT, Herskovits JS, Vallee RB (1995). "Molecular analysis of a cytoplasmic dynein light intermediate chain reveals homology to a family of ATPases". J. Cell Sci. 108 (1): 17–24. doi:10.1242/jcs.108.1.17. PMID 7738094.
• Chagnon P, Michaud J, Mitchell G, et al. (2003). "A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis". Am. J. Hum. Genet. 71 (6): 1443–9. doi:10.1086/344580. PMC 378590. PMID 12417987.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.