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DAK (gene)

From Wikipedia, the free encyclopedia
TKFC
Identifiers
AliasesTKFC, NET45, DAK, triokinase and FMN cyclase, TKFCD
External IDsOMIM: 615844; MGI: 2385084; HomoloGene: 56710; GeneCards: TKFC; OMA:TKFC - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_145496

RefSeq (protein)

NP_663471

Location (UCSC)Chr 11: 61.33 – 61.35 MbChr 19: 10.57 – 10.58 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Triokinase/FMN cyclase is an enzyme that in humans is encoded by the DAK gene.[5]

Function

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This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4',5'-phosphate (aka cyclic FMN) from FAD. Several alternatively spliced transcript variants have been identified, but the full-length nature of only one has been determined.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000149476Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034371Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: DAK dihydroxyacetone kinase 2 homolog (S. cerevisiae)".

Further reading

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