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Collagen triple helix repeat containing 1

From Wikipedia, the free encyclopedia
CTHRC1
Identifiers
AliasesCTHRC1, collagen triple helix repeat containing 1
External IDsOMIM: 610635; MGI: 1915838; HomoloGene: 16320; GeneCards: CTHRC1; OMA:CTHRC1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001256099
NM_138455

NM_026778
NM_001364812
NM_001364813

RefSeq (protein)

NP_001243028
NP_612464

NP_081054
NP_001351741
NP_001351742

Location (UCSC)Chr 8: 103.37 – 103.38 MbChr 15: 38.94 – 38.95 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Collagen triple helix repeat containing 1 is a protein that in humans is encoded by the CTHRC1 gene.[5]

Function

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This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett's esophagus and esophageal adenocarcinoma. Alternatively, spliced transcript variants have been described.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164932Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000054196Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Collagen triple helix repeat containing 1". Retrieved 2017-07-25.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.