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Charalampos Tzoulis

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Charalampos (Haris) Tzoulis is an internationally recognized expert in movement disorders and neurodegenerative diseases who has made several scientific contributions, especially in the understanding of mitochondrial dysfunction and NAD metabolism in Parkinson's disease.  

Education and career

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Tzoulis was born in Athens, Greece, studied medicine in Szeged, Hungary, and completed his specialization in neurology at Haukeland University Hospital, Bergen, Norway. In 2010 he obtained his PhD at the University of Bergen with the project: “Clinical and Molecular studies of Mitochondrial DNA Polymerase Gamma (POLG) Associated Disease”.[1] Currently, he is Professor of Neurology and Neurogenetics at the University of Bergen and Senior Consultant of Neurology at the Department of Neurology, Haukeland University Hospital.  

He leads the research group "DECODE-PD", [2] a transdisciplinary team of over 40 members focusing on translational and clinical research with the goal to develop and test new biomarkers and treatments for Parkinson's disease and related disorders. Their work comprises investigator-driven multicenter clinical trials, including a multi-arm multi-stage (MAMS) platform enabling parallel testing of multiple potential disease-modifying compounds.  

Tzoulis is co-Director (one of two) of the Neuro-SysMed National Center for Clinical Treatment Research in neurological diseases,[3] and director of the K.G. Jebsen Center for Translational Research in Parkinson's disease.[4]

Neuro-SysMed

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Prof. Tzoulis is the Head of the Neurodegeneration Research Program and Principal Investigator for Parkinson's Disease at the Neuro-SysMed Center. Neuro-SysMed is funded by the Norwegian Research Council [5] and conducts clinical research on four neurological disease-groups: Parkinson’s disease (PD) and related disorders, amyotrophic lateral sclerosis (ALS), dementia disorders, including Alzheimer’s disease and dementia with Lewy bodies, and multiple sclerosis (MS).

K.G. Jebsen Center for Parkinson’s Disease

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The overarching goal of the K.G. Jebsen Centre for Parkinson’s disease is to elucidate mechanisms driving the initiation and progression of Parkinson’s disease and related disorders and to identify molecular disease subtypes, so that tailored treatment may be developed and tested. This will enable design and test targeted therapies for each emerging molecular disease subtype, thus setting the foundation for tailored, personalized medicine for individuals with PD. The Center is funded by the K.G. Jebsen Foundation [6] together with the University of Bergen.

Publication record

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Prof. Tzoulis has led multiple publications in the field of neurodegeneration. [7]

Selected distinctions and awards

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  • 2024 - Member of the International Linked Clinical Trials (iLCT) committee for Parkinson’s disease [8]
  • 2018 - Falch Research Prize [9]
  • 2017 - Career Grant of the Trond Mohn Foundation (2017-2021) [10]
  • 2012 - Meltzer Young Researcher Award for outstanding scientific achievements by the University of Bergen in 2012 [11]
  • 2011 - Forsbergs & Aulies Legacy Grant [12]

References

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  1. ^ "Charalampos Tzoulis awarded prize for "Best PhD 2010"". University of Bergen. Retrieved 2025-03-17.
  2. ^ "Front Page - DECODE-PD". Retrieved 2025-03-17.
  3. ^ "Om oss". www.helse-bergen.no (in Norwegian Nynorsk). Retrieved 2025-03-17.
  4. ^ "K.G. Jebsen Centre for Translational Research in Parkinson's Disease - Stiftelsen Kristian Gerhard Jebsen". Retrieved 2025-03-17.
  5. ^ "Forskningssentre for klinisk behandling". www.forskningsradet.no (in Norwegian). Retrieved 2025-03-17.
  6. ^ "Nytt K.G. Jebsen-senter ved UiB skal forske på Parkinsons sykdom - Stiftelsen Kristian Gerhard Jebsen" (in Norwegian Bokmål). 2022-03-10. Retrieved 2025-03-17.
  7. ^ "charalampos tzoulis - Search Results - PubMed". PubMed. Retrieved 2025-03-17.
  8. ^ "The International Linked Clinical Trials (iLCT) programme". Cure Parkinson's. Retrieved 2025-03-17.
  9. ^ "Fakultetets dag 2018 | Det medisinske fakultet | UiB". web.archive.org. 2022-03-25. Retrieved 2025-03-17.
  10. ^ "Charalampos Tzoulis - Mohnfoundation" (in Norwegian Bokmål). Retrieved 2025-03-17.
  11. ^ "Charalampos Tzoulis awarded Meltzer Research Award". University of Bergen. Retrieved 2025-03-17.
  12. ^ "Nevrologistipendet 2011 | Forsbergs og Aulies legat" (in Norwegian Bokmål). Retrieved 2025-03-17.
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