CTBS

CTBS
Identifiers
Aliases	CTBS, CTB, chitobiase
External IDs	OMIM: 600873; MGI: 1921495; HomoloGene: 3231; GeneCards: CTBS; OMA:CTBS - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	84,574,480 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	146,171,604 bp
RNA expression pattern
	Top expressed in
	Epithelium of choroid plexus; ; monocyte; ; retinal pigment epithelium; ; blood; ; islet of Langerhans; ; stromal cell of endometrium; ; right lobe of liver; ; olfactory zone of nasal mucosa; ; Descending thoracic aorta; ; ascending aorta;
	Top expressed in
	proximal tubule; ; right kidney; ; granulocyte; ; human kidney; ; secondary oocyte; ; decidua; ; medullary collecting duct; ; liver; ; efferent ductule; ; primary oocyte;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	hydrolase activity, hydrolyzing O-glycosyl compounds; hydrolase activity; hydrolase activity, acting on glycosyl bonds; chitinase activity; chitin binding;
Cellular component	lysosome; extracellular exosome; extracellular space;
Biological process	oligosaccharide catabolic process; metabolism; chitin catabolic process; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	1486
	74245
	ENSG00000117151
	ENSMUSG00000028189
	Q01459
	Q8R242
	NM_004388
	NM_001293672; NM_028836
	NP_004379
	NP_001280601; NP_083112
	Wikidata
View/Edit Human	View/Edit Mouse

Di-N-acetylchitobiase is an enzyme that in humans is encoded by the CTBS gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000117151 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028189 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fisher KJ, Aronson NN Jr (Apr 1992). "Characterization of the cDNA and genomic sequence of a G protein gamma subunit (gamma 5)". Mol Cell Biol. 12 (4): 1585–91. doi:10.1128/mcb.12.4.1585. PMC 369601. PMID 1549114.
^ Ahmad W, Li S, Chen H, Tuck-Muller CM, Pittler SJ, Aronson NN Jr (Aug 1995). "Lysosomal chitobiase (CTB) and the G-protein gamma 5 subunit (GNG5) genes co-localize to human chromosome 1p22". Cytogenet Cell Genet. 71 (1): 44–6. doi:10.1159/000134059. PMID 7606925.
^ "Entrez Gene: CTBS chitobiase, di-N-acetyl-".

External links

Human CTBS genome location and CTBS gene details page in the UCSC Genome Browser.

Aronson NN, Halloran BA (2006). "Optimum substrate size and specific anomer requirements for the reducing-end glycoside hydrolase di-N-acetylchitobiase". Biosci. Biotechnol. Biochem. 70 (6): 1537–41. doi:10.1271/bbb.60183. PMID 16794344. S2CID 1848335.
Kamioka Y, Fukuhara S, Sawa H, et al. (2004). "A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis". J. Biol. Chem. 279 (38): 40091–9. doi:10.1074/jbc.M404899200. PMID 15252009.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hutchinson T, Dwivedi K, Rastogi A, et al. (2002). "N-acetyl beta-D-glucosaminidase is not attached to human sperm membranes through the glycosylphosphatidyl inositol (GPI)-anchor". Asian J. Androl. 4 (1): 27–33. PMID 11907625.
Liu B, Ahmad W, Aronson NN (1999). "Structure of the human gene for lysosomal di-N-acetylchitobiase". Glycobiology. 9 (6): 589–93. doi:10.1093/glycob/9.6.589. PMID 10336991.
Aronson NN, Backes M, Kuranda MJ (1989). "Rat liver chitobiase: purification, properties, and role in the lysosomal degradation of Asn-linked glycoproteins". Arch. Biochem. Biophys. 272 (2): 290–300. doi:10.1016/0003-9861(89)90222-1. PMID 2751306.
Fisher KJ, Aronson NN (1992). "Cloning and expression of the cDNA sequence encoding the lysosomal glycosidase di-N-acetylchitobiase". J. Biol. Chem. 267 (27): 19607–16. doi:10.1016/S0021-9258(18)41818-2. PMID 1527079.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000117151 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028189 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1549114-5] Fisher KJ, Aronson NN Jr (Apr 1992). "Characterization of the cDNA and genomic sequence of a G protein gamma subunit (gamma 5)". Mol Cell Biol. 12 (4): 1585–91. doi:10.1128/mcb.12.4.1585. PMC 369601. PMID 1549114.

[pmid7606925-6] Ahmad W, Li S, Chen H, Tuck-Muller CM, Pittler SJ, Aronson NN Jr (Aug 1995). "Lysosomal chitobiase (CTB) and the G-protein gamma 5 subunit (GNG5) genes co-localize to human chromosome 1p22". Cytogenet Cell Genet. 71 (1): 44–6. doi:10.1159/000134059. PMID 7606925.

[entrez-7] "Entrez Gene: CTBS chitobiase, di-N-acetyl-".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

References

External links

Further reading