From Wikipedia, the free encyclopedia
Protein-coding gene in humans
Copine-4 is a protein that in humans is encoded by the CPNE4 gene .[ 5] [ 6] [ 7]
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm .
This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus .[ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000196353 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032564 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Creutz CE, Tomsig JL, Snyder SL, Gautier MC, Skouri F, Beisson J, Cohen J (Feb 1998). "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans" . J Biol Chem . 273 (3): 1393–402. doi :10.1074/jbc.273.3.1393 PMID 9430674 . ^ Maitra R, Grigoryev DN, Bera TK, Pastan IH, Lee B (Apr 2003). "Cloning, molecular characterization, and expression analysis of Copine 8" . Biochem Biophys Res Commun . 303 (3): 842–7. doi :10.1016/S0006-291X(03)00445-5 . PMID 12670487 . ^ a b "Entrez Gene: CPNE4 copine IV" .
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