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CNOT9

From Wikipedia, the free encyclopedia
CNOT9
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCNOT9, CT129, RCD-1, RCD1, CAF40, RQCD1, CCR4-NOT transcription complex subunit 9
External IDsOMIM: 612054; MGI: 1928902; HomoloGene: 3973; GeneCards: CNOT9; OMA:CNOT9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001271634
NM_001271635
NM_005444

NM_021383

RefSeq (protein)

NP_001258563
NP_001258564
NP_005435

NP_067358

Location (UCSC)Chr 2: 218.57 – 218.6 MbChr 1: 74.55 – 74.57 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CCR4-NOT transcription complex subunit 9 is a protein that in humans is encoded by the CNOT9 gene. [5]

Function

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This gene encodes a member of the highly conserved RCD1 protein family. The encoded protein is a transcriptional cofactor and a core protein of the CCR4-Not deadenylation complex. It may be involved in signal transduction as well as retinoic acid-regulated cell differentiation and development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2012].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000144580Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026174Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: CCR4-NOT transcription complex subunit 9". Retrieved 2020-04-15.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.