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CLDN6

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CLDN6
Identifiers
AliasesCLDN6, claudin 6
External IDsOMIM: 615798; MGI: 1859284; HomoloGene: 10300; GeneCards: CLDN6; OMA:CLDN6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021195

NM_018777

RefSeq (protein)

NP_067018

NP_061247

Location (UCSC)Chr 16: 3.01 – 3.02 MbChr 17: 23.9 – 23.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Claudin-6 is a protein that in humans is encoded by the CLDN6 gene.[5][6][7] It belongs to the group of claudins. The knockout mice of mouse homolog exhibit no phenotype, indicating that claudin-6 is dispensable for normal development and homeostasis.


References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000184697Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023906Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Morita K, Furuse M, Fujimoto K, Tsukita S (Mar 1999). "Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands". Proc Natl Acad Sci U S A. 96 (2): 511–6. Bibcode:1999PNAS...96..511M. doi:10.1073/pnas.96.2.511. PMC 15167. PMID 9892664.
  6. ^ Meertens L, Bertaux C, Cukierman L, Cormier E, Lavillette D, Cosset FL, Dragic T (Mar 2008). "The Tight Junction Proteins Claudin-1, -6, and -9 Are Entry Cofactors for Hepatitis C Virus". J Virol. 82 (7): 3555–60. doi:10.1128/JVI.01977-07. PMC 2268462. PMID 18234789.
  7. ^ "Entrez Gene: CLDN6 claudin 6".
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Further reading

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