From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Centrosomal protein of 55 kDa (Cep55) , is a protein that in humans is encoded by the CEP55 gene .[ 5] [ 6]
Cep55 is a mitotic phosphoprotein that plays a key role in cytokinesis , the final stage of cell division.[ 7] and cilia formation in neural stem cells.[ 8]
^ a b c GRCh38: Ensembl release 89: ENSG00000138180 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024989 – Ensembl , May 2017
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^ Fabbro M, Zhou BB, Takahashi M, Sarcevic B, Lal P, Graham ME, Gabrielli BG, Robinson PJ, Nigg EA, Ono Y, Khanna KK (Oct 2005). "Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis" . Dev Cell . 9 (4): 477–88. doi :10.1016/j.devcel.2005.09.003 . PMID 16198290 .
^ "Entrez Gene: CEP55 centrosomal protein 55kDa" .
^ van der Horst A, Simmons J, Khanna KK (November 2009). "Cep55 stabilization is required for normal execution of cytokinesis" . Cell Cycle . 8 (22): 3742–3749. doi :10.4161/cc.8.22.10047 . PMID 19855176 .
^ Behnam Rashidieh; Belal Shohayeb; Amanda Louise Bain; Patrick R. J. Fortuna; Debottam Sinha; Andrew Burgess; Richard Mills; Rachael C. Adams; J. Alejandro Lopez; Peter Blumbergs; John Finnie; Murugan Kalimutho; Michael Piper; James Edward Hudson; Dominic C. H. Ng; Kum Kum Khanna (October 2021). "Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis" . PLOS Genetics . 17 (10): e1009334. doi :10.1371/journal.pgen.1009334 . PMC 8577787 . PMID 34710087 .
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