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Protein-coding gene in humans
Cdc42 effector protein 4 is a protein that in humans is encoded by the CDC42EP4 gene .[ 5] [ 6] [ 7]
The product of this gene is a member of the CDC42 -binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton . This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP -dependent manner. When overexpressed in fibroblasts , this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.[ 7]
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