Caspase 5
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caspase 5, apoptosis-related cysteine peptidase | |||||||
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Identifiers | |||||||
Symbol | CASP5 | ||||||
Alt. symbols | ICE(rel)III, ICH3 | ||||||
NCBI gene | 838 | ||||||
HGNC | 1506 | ||||||
OMIM | 602665 | ||||||
RefSeq | NM_004347 | ||||||
UniProt | P51878 | ||||||
Other data | |||||||
EC number | 3.4.22.58 | ||||||
Locus | Chr. 11 q22.2-q22.3 | ||||||
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Caspase 5 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system.[1]
See also
[edit]References
[edit]- ^ Martinon F, Tschopp J (2007). "Inflammatory caspases and inflammasomes: master switches of inflammation". Cell Death Differ. 14 (1): 10–22. doi:10.1038/sj.cdd.4402038. PMID 16977329.
External links
[edit]- The MEROPS online database for peptidases and their inhibitors: C14.008[permanent dead link ]