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Ann English

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Ann Marie English
Alma materMcGill University
University College Dublin
Known forBioinorganic Chemistry
Mass Spectrometry
Scientific career
InstitutionsConcordia University
ThesisSpectral Studies on Group VIB Metal Chalcocarbonyls (1980)
Doctoral advisorIan S. Butler

Ann Marie English is an Irish Canadian scientist in bioinorganic chemistry and redox biology, recognized for her contribution to chemistry in Canada.[1]

Education

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English received a BSc from University College Dubin in Ireland in 1971 and a PhD in Inorganic Chemistry from McGill University in Canada in 1980.[2]

Career

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After graduation, English did post-doctoral research at California Institute of Technology as a research fellow in chemistry.[3] Under the direction of Harry B. Gray, she conducted research on electron transfer of copper proteins.[4] She began her academic career at Concordia University as assistant professor in 1982[5] and was promoted to full professor in 1994.[2] Since 2018, she is Distinguished Professor Emerita and Honorary Concordia University Research Chair in the Department of Chemistry and Biochemistry at Concordia University.[6] She has mentored over 55 graduate students and 37 postdoctoral fellows and researchers.[7]

Her research field is in heme-protein chemistry and biochemistry,[8][9][10] including the effects of metal-induced oxidation on aging at the cellular level.[11][12][13] She has published over 130 peer-reviewed journal articles and book chapters.[14] With mass spectrometry being one of the techniques used in her research,[15][16][17] she established the Centre for Biological Applications of Mass Spectrometry in 2003.[7]

She was elected as Fellow of the Chemical Institute of Canada in 2014[18] and Fellow of the Royal Society of Canada Academy of Science in 2024.[19][20]

Awards

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References

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  1. ^ a b "Clara Benson Award". The Chemical Institute of Canada. Retrieved 2025-01-02.
  2. ^ a b "Ann English - Concordia University". www.concordia.ca. Retrieved 2025-01-02.
  3. ^ "INFORMATION FOR STUDENTS 1980-81" (PDF). CALIFORNIA INSTITUTE OF TECHNOLOGY. September 1980. Retrieved 2025-01-01.
  4. ^ English, Ann M.; DeLaive, Patricia J.; Gray, Harry B.; Lum, Vanessa R. (1982-02-01). "Metalloprotein electron-transfer mechanisms. Quenching of electronically excited tris(2,2'-bipyridine)ruthenium(II) by reduced blue copper proteins". Journal of the American Chemical Society. 104 (3): 870–871. Bibcode:1982JAChS.104..870E. doi:10.1021/ja00367a047. ISSN 0002-7863.
  5. ^ "A celebration of internal research awards - Concordia Journal - Concordia University - Montreal, Quebec, Canada". cjournal.concordia.ca. Retrieved 2025-01-02.
  6. ^ "Faculty members - Concordia University". www.concordia.ca. Retrieved 2025-01-02.
  7. ^ a b Miller, Harry (2024-02-20). "Concordia's Ann English wins Lifetime Achievement Award for her seminal work in bioinorganic chemistry – Concordia University News". Canada News Media. Retrieved 2025-01-02.
  8. ^ Smulevich, Giulietta; Mauro, J. Matthew; Fishel, Laurence A.; English, Ann M.; Kraut, Joseph; Spiro, Thomas G. (1988-07-01). "Heme pocket interactions in cytochrome c peroxidase studied by site-directed mutagenesis and resonance Raman spectroscopy". Biochemistry. 27 (15): 5477–5485. doi:10.1021/bi00415a014. ISSN 0006-2960. PMID 2846039.
  9. ^ English, Ann M.; Tsaprailis, George (1995-01-01), Sykes, A. G. (ed.), Catalytic Structure–Function Relationships in Heme Peroxidases, Advances in Inorganic Chemistry, vol. 43, Academic Press, pp. 79–125, doi:10.1016/s0898-8838(08)60116-6, ISBN 978-0-12-023643-5, retrieved 2025-01-02
  10. ^ Shadrina, Maria S.; Laterreur, Julie; Peslherbe, Gilles H.; English, Ann M. (2024). "Hemoglobin's β-subunit is primed to synergize oxygen delivery with nitric oxide-mediated increased blood flow". Journal of Porphyrins and Phthalocyanines. 28 (6): 370–382. doi:10.1142/S1088424624500305. ISSN 1088-4246.
  11. ^ "Unlocking the secrets of aging - Concordia University". www.concordia.ca. Retrieved 2025-01-02.
  12. ^ Martins, Dorival; English, Ann M. (2012-11-01). "Cysteine 146 of CuZnSOD is Oxidized to Sulfonic Acid During Aging of Yeast: A Potential Mechanism Underlying Sporadic ALS Onset". Free Radical Biology and Medicine. SFRBM's 19th Annual Meeting: Program and Abstracts. 53: S126. doi:10.1016/j.freeradbiomed.2012.10.313. ISSN 0891-5849.
  13. ^ English, Ann M (2010-01-01). "The Heme Peroxidase CCP is Released from Mitochondria during Chronological Aging of Yeast". Free Radical Biology and Medicine. SFRBM's 17th Annual Meeting: Program and Abstracts. 49: S79. doi:10.1016/j.freeradbiomed.2010.10.196. ISSN 0891-5849.
  14. ^ "Ann English". scholar.google.com. Retrieved 2025-01-02.
  15. ^ Jahangiri, Soran; Timerghazin, Qadir K.; Jiang, Heng; Peslherbe, Gilles H.; English, Ann M. (2018-06-01). "Dramatic CC bond activation on protonation of the persistent nitroxyl radical TEMPO". International Journal of Mass Spectrometry. Terry B. McMahon 70th Birthday Special Issue: Mass Spectrometry and its Application to the Physical Chemistry of Gaseous Ions. 429: 182–188. Bibcode:2018IJMSp.429..182J. doi:10.1016/j.ijms.2017.08.007. ISSN 1387-3806.
  16. ^ Kathiresan, Meena; English, Ann M. (2017-01-30). "LC-MS/MS suggests that hole hopping in cytochrome c peroxidase protects its heme from oxidative modification by excess H2O2". Chemical Science. 8 (2): 1152–1162. doi:10.1039/C6SC03125K. ISSN 2041-6539. PMC 5369544. PMID 28451256.
  17. ^ Papp, Robert; Ekiel, Irena; English, Ann M (2003). "ESI-MS and FTIR studies of the interaction between the second PDZ domain of hPTP1E and target peptides". Biochemistry and Cell Biology. 81 (2): 71–80. doi:10.1139/o03-036. ISSN 0829-8211. PMID 12870871.
  18. ^ "CIC Fellows" (PDF). Chemical Institute of Canada. Retrieved 2025-01-01.
  19. ^ "Concordia celebrates a record year at the Royal Society of Canada - Concordia University". www.concordia.ca. Retrieved 2025-01-02.
  20. ^ "ROYAL SOCIETY OF CANADA - CLASS OF 2024" (PDF). ROYAL SOCIETY OF CANADA. Retrieved 2025-01-01.
  21. ^ "Society of Porphyrins & Phthalocyanines". www.icpp-spp.org. Retrieved 2025-01-02.
  22. ^ "Lossing Award". csms.clientwebdev.com. Retrieved 2025-01-02.
  23. ^ Oct 12; Finalists, 2018 | Outstanding Graduate Mentorship; Prizes. "Finalist – 2018 Award for Outstanding Graduate Mentorship – Dr. Ann English | CAGS | ACES". Retrieved 2025-01-02.{{cite web}}: CS1 maint: numeric names: authors list (link)
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