Jump to content

α-amyrin synthase

From Wikipedia, the free encyclopedia
(Redirected from Alpha-amyrin synthase)
α-Amyrin synthase
Identifiers
EC no.5.4.99.40
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

α-Amyrin synthase (EC 5.4.99.40, 2,3-oxidosqualene alpha-amyrin cyclase, mixed amyrin synthase) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, alpha-amyrin-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene alpha-amyrin

This multifunctional enzyme produces both alpha- and beta-amyrin.

References

[edit]
  1. ^ Morita M, Shibuya M, Kushiro T, Masuda K, Ebizuka Y (June 2000). "Molecular cloning and functional expression of triterpene synthases from pea (Pisum sativum) new alpha-amyrin-producing enzyme is a multifunctional triterpene synthase". European Journal of Biochemistry. 267 (12): 3453–60. doi:10.1046/j.1432-1327.2000.01357.x. PMID 10848960.
[edit]