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Alimadol

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Not to be confused with adimolol.
Alimadol
Clinical data
ATC code
  • None
Identifiers
  • N-(3-methoxy-3,3-diphenylpropyl)-2-propen-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H23NO
Molar mass281.399 g·mol−1
3D model (JSmol)
  • O(C)C(c1ccccc1)(c2ccccc2)CCNC\C=C
  • InChI=1S/C19H23NO/c1-3-15-20-16-14-19(21-2,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h3-13,20H,1,14-16H2,2H3
  • Key:QFSWEWNANAHUNE-UHFFFAOYSA-N

Alimadol (INN; A-4020) is an opioid analgesic related to methadone which was never marketed.[1]

Synthesis

[edit]
Patent:[2] Precursor (benzyl group sidechain):[3]
  • benzhydryl methyl ether [1016-09-7] (1)
  • β-chloroethylamine [689-98-5] (2)
  • 1,1-Diphenyl-1-methoxy-3-aminopropane: PC21534188 (3)
  • Allyl bromide [106-95-6] (4)

See also

[edit]

References

[edit]
  1. ^ Ganellin CR, Triggle DJ (1997). Dictionary of Pharmacological Agents. CRC Press. p. 47. ISBN 978-0-412-46630-4. Retrieved 11 May 2012.
  2. ^ US 3960960, Hollinger R, Wendtlandt W, Schneider G, "1,1-Diphenyl-1-lower alkoxy-amino-alkanes and the salts thereof", issued 1 June 1976, assigned to Chemie Linz AG 
  3. ^ Hoellinger Roderich Dr, CH478088A (1969 to Chemie Linz Ag).



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