algC RNA motif
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|
| algC | |
|---|---|
 Consensus secondary structure and sequence conservation of algC RNA | |
| Identifiers | |
| Symbol | algC |
| Rfam | RF02929 |
| Other data | |
| RNA type | Cis-reg |
| SO | SO:0005836 |
| PDB structures | PDBe |
The algC RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] algC motifs are found in Enterobacteriaceae.
algC motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. Indeed, most examples of the motif are found upstream of 'algC' genes, which are known to encode phosphomannomutases or phosphoglucomutases. However, in rare examples, it is associated with other genes whose protein products are involved in sugar metabolism. These other genes encode UDP-glucose phosphotransferase and polysaccharide pyruvyl transferase. Thus, the motif might have a regulatory role related to a specific type of sugar-related molecule.
References
[edit]- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.