ARL8B

ARL8B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2AL7
Identifiers
Aliases	ARL8B, ARL10C, Gie1, ADP ribosylation factor like GTPase 8B
External IDs	OMIM: 616596; MGI: 1914416; HomoloGene: 10056; GeneCards: ARL8B; OMA:ARL8B - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	5,180,911 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	108,802,239 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; Brodmann area 23; ; lateral nuclear group of thalamus; ; postcentral gyrus; ; amniotic fluid; ; Brodmann area 46; ; Pons; ; orbitofrontal cortex; ; gingival epithelium; ; entorhinal cortex;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; muscle of thigh; ; subiculum; ; tail of embryo; ; anterior amygdaloid area; ; olfactory tubercle; ; ventral tegmental area; ; dorsomedial hypothalamic nucleus; ; prefrontal cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GDP binding; alpha-tubulin binding; GTP binding; GTPase activity; beta-tubulin binding; protein binding;
Cellular component	cytoplasm; endosome; membrane; late endosome membrane; spindle; intracellular anatomical structure; midbody; spindle midzone; lysosome; extracellular exosome; cytoskeleton; lysosomal membrane; vacuolar membrane; axon; synapse; axon cytoplasm; cell junction; cell projection;
Biological process	chromosome segregation; small GTPase mediated signal transduction; cell division; cell cycle; lysosome localization; anterograde axonal transport; protein transport;
	Sources:Amigo / QuickGO
Orthologs
	55207
	67166
	ENSG00000134108
	ENSMUSG00000030105
	Q9NVJ2
	Q9CQW2
	NM_018184
	NM_026011
	NP_060654
	NP_080287
	Wikidata
View/Edit Human	View/Edit Mouse

ADP-ribosylation factor-like protein 8B is a protein that in humans is encoded by the ARL8B gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000134108 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030105 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
^ "Entrez Gene: ARL8B ADP-ribosylation factor-like 8B".

External links

Human ARL8B genome location and ARL8B gene details page in the UCSC Genome Browser.

Bagshaw RD, Callahan JW, Mahuran DJ (2006). "The Arf-family protein, Arl8b, is involved in the spatial distribution of lysosomes". Biochem. Biophys. Res. Commun. 344 (4): 1186–91. doi:10.1016/j.bbrc.2006.03.221. PMID 16650381.
Hofmann I, Munro S (2006). "An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility". J. Cell Sci. 119 (Pt 8): 1494–503. doi:10.1242/jcs.02958. PMID 16537643.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells" (PDF). Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788. Archived from the original (PDF) on 2019-02-24.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Okai T, Araki Y, Tada M, et al. (2005). "Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation". J. Cell Sci. 117 (Pt 20): 4705–15. doi:10.1242/jcs.01347. PMID 15331635.
Secombe J, Parkhurst SM (2004). "Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein". J. Biol. Chem. 279 (17): 17126–33. doi:10.1074/jbc.M310097200. PMID 14871887.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000134108 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030105 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12477932-5] Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

[entrez-6] "Entrez Gene: ARL8B ADP-ribosylation factor-like 8B".

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[2]

[3]

[4]

[5]

[6]

References

External links

Further reading