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4'-Methoxy-α-pyrrolidinopentiophenone

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(Redirected from 4-MeO-α-PVP)
4'-Methoxy-α-pyrrolidinopentiophenone
Legal status
Legal status
Identifiers
  • 1-(4-Methoxyphenyl)-2-(pyrrolidin-1-yl)pentan-1-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H23NO2
Molar mass261.365 g·mol−1
3D model (JSmol)
  • COC1=CC=C(C(C(CCC)N2CCCC2)=O)C=C1.Cl
  • InChI=1S/C16H23NO2/c1-3-6-15(17-11-4-5-12-17)16(18)13-7-9-14(19-2)10-8-13/h7-10,15H,3-6,11-12H2,1-2H3
  • Key:HWYVHRCKBXGZLV-UHFFFAOYSA-N

4'-Methoxy-α-pyrrolidinopentiophenone (also known as O-2417, 4-MeO-α-PVP and MOPVP) is a stimulant drug of the cathinone class that has been sold online as a designer drug.[1][2][3][4][5]

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As of October 2015 4-MeO-α-PVP is a controlled substance in China.[6]

See also

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References

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  1. ^ "4-methoxy-α-Pyrrolidinopentiophenone". Cayman Chemical. Archived from the original on 8 December 2015. Retrieved 5 August 2015.
  2. ^ Meltzer PC, Butler D, Deschamps JR, Madras BK (February 2006). "1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors". Journal of Medicinal Chemistry. 49 (4): 1420–32. doi:10.1021/jm050797a. PMC 2602954. PMID 16480278.
  3. ^ US 2008234498, Butler D, Madras BK, Meltzer PC, "Pyrovalerone Analogues and Therapeutic Uses Thereof", issued 25 September 2008 
  4. ^ Uchiyama N, Matsuda S, Kawamura M, Kikura-Hanajiri R, Goda Y (January 2014). "Identification of two new-type designer drugs, piperazine derivative MT-45 (I-C6) and synthetic peptide Noopept (GVS-111), with synthetic cannabinoid A-834735, cathinone derivative 4-methoxy-α-PVP, and phenethylamine derivative 4-methylbuphedrine from illegal products". Forensic Toxicology. 32 (1): 9–18. doi:10.1007/s11419-013-0194-5. S2CID 37259772.
  5. ^ Ellefsen KN, Wohlfarth A, Swortwood MJ, Diao X, Concheiro M, Huestis MA (August 2015). "4-Methoxy-α-PVP: in silico prediction, metabolic stability, and metabolite identification by human hepatocyte incubation and high-resolution mass spectrometry". Forensic Toxicology. 34: 61–75. doi:10.1007/s11419-015-0287-4. PMC 4705136. PMID 26793277.
  6. ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.