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2'-Deamino-2'-hydroxyneamine transaminase

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2'-Deamino-2'-hydroxyneamine transaminase
Identifiers
EC no.2.6.1.94
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

2'-Deamino-2'-hydroxyneamine transaminase (EC 2.6.1.94, kacL (gene)) is an enzyme with systematic name 2'-deamino-2'-hydroxyneamine:2-oxoglutarate aminotransferase.[1] This enzyme catalyses the following chemical reaction

2'-deamino-2'-hydroxyneamine + 2-oxoglutarate 2'-deamino-2'-hydroxy-6'-dehydroparomamine + L-glutamate

The reaction occurs in vivo in the opposite direction.

References

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  1. ^ Park JW, Park SR, Nepal KK, Han AR, Ban YH, Yoo YJ, Kim EJ, Kim EM, Kim D, Sohng JK, Yoon YJ (October 2011). "Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation". Nature Chemical Biology. 7 (11): 843–52. doi:10.1038/nchembio.671. PMID 21983602.
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