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α-Ketovaleric acid

From Wikipedia, the free encyclopedia
α-Ketovaleric acid
Names
Preferred IUPAC name
2-Oxopentanoic acid
Other names
α-Ketovalerate; α-Oxovaleric acid; 2-Ketopentanoic acid; 2-Oxo-n-valeric acid
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.015.764 Edit this at Wikidata
UNII
  • InChI=1S/C5H8O3/c1-2-3-4(6)5(7)8/h2-3H2,1H3,(H,7,8) checkY
    Key: KDVFRMMRZOCFLS-UHFFFAOYSA-N checkY
  • InChI=1S/C5H8O3/c1-2-3-4(6)5(7)8/h2-3H2,1H3,(H,7,8)
  • O=C(C(=O)O)CCC
Properties
C5H8O3
Molar mass 116.116 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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α-Ketovaleric acid is a keto acid that is found in human blood.[1][2][3] Unlike related keto acids, it is not an intermediate or metabolite associated with amino acids and its origin is unknown.[4]

See also

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References

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  1. ^ Fu, X; Kimura, M; Iga, M; Yamaguchi, S (2001). "Gas chromatographic-mass spectrometric screening for organic acidemias using dried urine filter paper: determination of alpha-ketoacids". Journal of Chromatography B. 758 (1): 87–94. doi:10.1016/s0378-4347(01)00101-3. PMID 11482739.
  2. ^ Lee, SH; Kim, SO; Chung, BC (1998). "Gas chromatographic-mass spectrometric determination of urinary oxoacids using O-(2,3,4,5,6-pentafluorobenzyl)oxime-trimethylsilyl ester derivatization and cation-exchange chromatography". Journal of Chromatography B. 719 (1–2): 1–7. doi:10.1016/s0378-4347(98)00388-0. PMID 9869358.
  3. ^ Wang, ZJ; Zaitsu, K; Ohkura, Y (1988). "High-performance liquid chromatographic determination of alpha-keto acids in human serum and urine using 1,2-diamino-4,5-methylenedioxybenzene as a precolumn fluorescence derivatization reagent". Journal of Chromatography. 430 (2): 223–31. doi:10.1016/s0378-4347(00)83157-6. PMID 3235498.
  4. ^ European Nutrigenomics Organisation Metabolite Database