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Selenium responsive proteins

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Selenium responsive proteins within human biology, are the class of proteins sensitive to selenium, in healthy human beings, in cancer patients, in in-vivo models or in-vitro cell culture models.

The original gi accession (version) numbers have been updated to NCBI accession number and protein names updated accordingly.[clarification needed]

Accession Number Common abbreviation Protein name Responsive in Selenium compound technique used source
Q08091 CNN1 Calponin-1 TRAMP (prostate cancer mouse model) MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
NP_035656 TAGLN Transgelin TRAMP (prostate cancer mouse model) MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
NP_033822 APOA1 Apolipoprotein A-I TRAMP (prostate cancer mouse model) MSeC, MseA iTRAQ LC-MS/MS Zhang 2010 [1]
NP_038499 ANXA4 Annexin A4 TRAMP (prostate cancer mouse model) MseA iTRAQ LC-MS/MS Zhang 2010 [1]
gi21071030 A1BG Alpha 1B-glycoprotein Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2]
gi4557871 TF Transferrin Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2]
gi4502501 C4b Complement component 4B proprotein Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2]
NP_059086 SEMG1 semenogelin I TRAMP DLP UP MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
CAA47699 BGPG Biliary glycoprotein TRAMP DLP UP MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
NP_780375 BASP1 brain acid soluble protein 1 TRAMP DLP UP MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
NP_031789 Cysteine-rich protein 1 TRAMP DLP UP MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
NP_059067 HPX Hemopexin TRAMP DLP UP MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi7305531 Seminal vesicle secretion 6 TRAMP DLP UP MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
NP_780375 DMBTL_MOUSE putative DMBT1-like protein precursor TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi6755212 Proteasome (prosome, macropain) 28 subunit, α TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
NP_035309 PSAP Prosaposin TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi123794006 FUSE-binding protein 2 TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi84875537 Nucleolin TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi40254525 Tropomyosin 3, gamma TRAMP DLP UP MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
NP_032775 NUCB1 Nucleobindin 1 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi94717635 Progesterone receptor membrane component TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi21704156 Caldesmon 1 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi31980648 ATP synthase, H+ transporting mitochondrial F1 complex β TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi10946574 Creatine kinase, brain TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi94367355 Similar to 60S ribosomal protein L5 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi31981520 Pancreatic ribonuclease TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi6754084 Glutathione S-transferase, mu 1 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi6680121 Glutathione S-transferase, μ 2 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi31981302 Annexin A6 TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi6678740 Lumican TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi94403723 Similar to Heat shock 70-kDa protein 1B (HSP70.1) TRAMP DLP DOWN MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi89574165 Succinate dehydrogenase complex subunit A TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi70778915 Moesin TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi6679567 Polymerase I and transcript release factor TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi31791059 Activated leukocyte cell adhesion molecule TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi76779293 Keratin 8 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi6671549 Peroxiredoxin 6 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi6680836 Calreticulin TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
NP_808579 TGM4 protein-glutamine gamma-glutamyltransferase 4 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi8567372 Probasin TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi2506545 78-kDa glucose-regulated protein precursor (GRP 78) TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi7643979 170-kDa glucose regulated protein GRP170 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi31542563 DnaJ (Hsp40) homolog, subfamily C, member 3 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi71774133 Peptidylprolyl isomerase B (PPI) TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi130232 Protein disulfide isomerase b family, ERp57 subfamily TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi129729 Protein disulfide isomerase ERp59 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi86198316 Protein disulfide isomerase associated 4 TRAMP DLP DOWN MSeA iTRAQ LC-MS/MS Zhang 2010 [1]
gi58037267 Protein disulfide isomerase-associated 6 TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi6753010 Anterior gradient 2 TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi42794267 Experimental autoimmune prostatitis antigen 2 TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi31543942 Vinculin TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi94387119 PREDICTED: similar to heat shock protein 8 TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi6752952 Actin, γ2, smooth muscle, enteric TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi94381948 PREDICTED: similar to Fc fragment of IgG binding protein TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi6754482 Keratin complex 1, acidic, gene 18 TRAMP DLP DOWN MSeA, MSeC iTRAQ LC-MS/MS Zhang 2010 [1]
gi5031777 isocitrate dehydrogenase Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2]
NP_005134 HP Haptoglobin isoform 1 preproprotein Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2]
gi42716297 CLU Clusterin isoform 1 Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2]
gi17318569 Keratin 1 Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2]
gi4507725 Transthyretin Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2]
gi21361198 AAT Alpha-1 antitrypsin Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2]
gi4557287 Angiotensin precursor Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2]
gi4502027 Albumin precursor Healthy Human blood serum Selenium enriched yeast 2D DIGE LC-MS/MS Sinha 2010 [2]

References

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  1. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az Zhang, J.; Wang, L.; Anderson, L. B.; Witthuhn, B.; Xu, Y.; Lu, J. (2010). "Proteomic Profiling of Potential Molecular Targets of Methyl-Selenium Compounds in the Transgenic Adenocarcinoma of Mouse Prostate Model". Cancer Prevention Research. 3 (8): 994–1006. doi:10.1158/1940-6207.CAPR-09-0261. PMID 20647336.
  2. ^ a b c d e f g h i j k Sinha, R.; Sinha, I.; Facompre, N.; Russell, S.; Somiari, R.; Richie Jr, J.; El-Bayoumy, K. (2010). "Selenium responsive proteins in sera of selenium-enriched yeast supplemented healthy African American and Caucasian men". Cancer Epidemiology, Biomarkers & Prevention. 19 (9): 2332–2340. doi:10.1158/1055-9965.EPI-10-0253. PMC 3326597. PMID 20643827.