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Yunnanxane

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Yunnanxane
Names
Systematic IUPAC name
2,5,10-Triacetoxytaxa-4(20),11-dien-14-yl 3-hydroxy-2-methylbutanoate
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • CC1(C)C([C@@H](OC(C)=O)C[C@@]2(C)[C@](C([C@@H](OC(C)=O)CC2)=C)([H])[C@@H]3OC(C)=O)=C(C)[C@@H](OC([C@H](C)[C@H](C)O)=O)C[C@]13[H]
Properties
C31H46O9
Molar mass 562.700 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Yunnanxane is a bioactive taxane diterpenoid first isolated from Taxus wallichiana. Yunnanxane was later isolated from cell cultures of Taxus cuspidata and Taxus chinensis. Four homologous esters of yunnanxane have also been isolated from Taxus. Yunnanxane is reported to have anticancer activity in vitro.[1][2]

See also

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References

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  1. ^ Chen WM, Zhang PL, Wu B, Zheng QT (1991). "[Studies on the chemical constituents of Taxus yunnanensis]". Yao Xue Xue Bao. 26 (10): 747–54. PMID 1688071.
  2. ^ Ma W, Stahlhut RW, Adams TL, Park GL, Evans WA, Blumenthal SG, et al. (1994). "Yunnanxane and its homologous esters from cell cultures of Taxus chinensis var. mairei". J Nat Prod. 57 (9): 1320–4. doi:10.1021/np50111a027. PMID 7798969.