The 1916 United States House of Representatives elections in South Carolina were held on November 7, 1916, to select seven Representatives for two-year terms from the state of South Carolina. The primary elections were held on August 29 and the runoff elections were held two weeks later on September 12. Six incumbents were re-elected, but Wyatt Aiken of the 3rd congressional district was defeated in the Democratic primary. The seat was retained by the Democrats and the composition of the state delegation remained solely Democratic.
Incumbent Democratic Congressman Richard S. Whaley of the 1st congressional district, in office since 1913, defeated James G. Padgett in the Democratic primary and Republican J.O. Ladd in the general election.
Incumbent Democratic Congressman James F. Byrnes of the 2nd congressional district, in office since 1911, defeated Alvin Etheredge in the Democratic primary and Republican Isaac Myers in the general election.
Incumbent Democratic Congressman Samuel J. Nicholls of the 4th congressional district, in office since 1915, won the Democratic primary and defeated Republican G.F. Mills in the general election.
Incumbent Democratic Congressman J. Willard Ragsdale of the 6th congressional district, in office since 1913, won the Democratic primary and defeated Republican W.L. McFarlan in the general election.
Jordan, Frank E. The Primary State: A History of the Democratic Party in South Carolina, 1876-1962. pp. 98, 101, 105, 110, 115, 119.
"Report of the Secretary of State to the General Assembly of South Carolina. Part II." Reports and Resolutions of the General Assembly of the State of South Carolina. Volume II. Columbia, SC: 1917, pp. 3–4.