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Uncinate process of pancreas

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Uncinate process of pancreas
Details
Arterysuperior mesenteric artery
Identifiers
Latinprocessus uncinatus pancreatis
TA98A05.9.01.003
TA23116
FMA15857
Anatomical terminology

The uncinate process is a small part of the pancreas. The uncinate process is the formed prolongation of the angle of junction of the lower and left lateral borders in the head of the pancreas. The word "uncinate" comes from the Latin "uncinatus", meaning "hooked".[1]

Structure

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Development

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The pancreas arises as two separate bodies, the dorsal pancreas and the ventral pancreas. The dorsal pancreas appears first, at around day 26, opposite the developing hepatic duct, and grows into the dorsal mesentery. The ventral pancreas develops at the junction of the hepatic duct and the rest of the foregut.

During development, differential growth of the wall of the stomach causes it to rotate to the left, and the liver and stomach undergo a lot of growth. This makes the two parts of the pancreas rotate around the duodenum. They then fuse; the dorsal pancreatic bud becomes the body, tail, and isthmus of the pancreas. The isthmus (also called the central pancreas) is the region of the gland that runs anterior to the superior mesenteric artery; by convention, it divides the right and left sides of the pancreas.[2]

The ventral pancreatic bud forms the pancreatic head and uncinate process. The glands continue to develop but the duct systems anastomose. The main pancreatic duct is formed by the fusion of the dorsal and ventral pancreas.

The embryology also explains the strange zig-zag course of the main pancreatic duct and the occasional appearance of an accessory pancreatic duct.

The uncinate process, unlike the remainder of the organ, passes posteriorly to the superior mesenteric vein (it can pass posteriorly to the superior mesenteric artery, but this is less common).

Clinical significance

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Sometimes the pancreas fails to develop normally and there may be congenital defects associated with the uncinate process. The uncinate process may split and encircle the duodenum, which is known as an annular pancreas.[3] There is also a common condition called pancreas divisum where the dorsal and ventral pancreas do not fuse properly.

References

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Public domain This article incorporates text in the public domain from page 1200 of the 20th edition of Gray's Anatomy (1918)

  1. ^ "Arnold's Glossary of Anatomy". Archived from the original on 2018-10-31.
  2. ^ Hac, Stanisław A.; Dobosz, Marek; Nalecz, Adam; Reszetow, Jacek; Dobrowolski, Sebastian; Friess, Helmut; Michaljevic, Andre L.; Mroczkowski, Pawel; Studniarek, Michal; Sledzinski, Zbigniew (17 May 2010). "Surgical Morphology of the Pancreatic Isthmus" (PDF). Pancreatology. 10 (2–3): 179–85. doi:10.1159/000231983. PMID 20484956. S2CID 40495444. Archived from the original (PDF) on 21 January 2019.
  3. ^ Drake et al, Gray's Anatomy for Students, Churchill Livingstone/Elsevier (2010), 2nd edition, chapter 4
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